细胞因子与寄生虫感染关系研究进展  

Advances in research on the relationship between cytokines and parasite immunity

作　　者：程云[1,2] 李建华[1] 彭景贤[3] 

机构地区：[1]贵阳医学院寄生虫学教研室,贵州贵阳550004 [2]包头医学院组织学与胚胎学教研室,内蒙古包头014060 [3]包头市疾病预防控制中心微生物检验科,内蒙古包头014030

出　　处：《中国病原生物学杂志》2010年第5期381-384,共4页Journal of Pathogen Biology

基　　金：贵州省高校发展专项资金资助自然科学类科研项目(No.2004116)

摘　　要：寄生虫感染均不同程度地伴随免疫损伤,宿主在感染寄生虫后产生的免疫应答中,细胞因子作为介质起着关键作用。本文综述了细胞因子在寄生虫感染中对免疫应答的调节、抗虫和病理损害作用机制,并对寄生虫感染引起的细胞因子变化及免疫逃避机制进行探讨,为寄生虫病免疫诊断、治疗及预防提供依据。Parasitic infections are associated with varying degrees of immune damage. The host produces an immune response after being infected with a parasite,and cytokines play a key role in this response. This paper summarizes the mechanisms by which cytokines regulate immune response,resist parasites,and cause pathological changes during parasitic infections. This paper also explores the changes in cytokines caused by parasitic infection and mechanisms of immune evasion by parasite. This work should provide a basis for the immunodiagnosis,treatment,and prevention of parasitic disease.

关 键 词：寄生虫感染 细胞因子 综述 

分 类 号：R38[医药卫生—医学寄生虫学]