正交试验法优化丹参总酮提取工艺  

Optimization of Extracting Technology of Total Tanshinone in Salviae Miltiorrhiza by the Orthogonal Experment

作　　者：王小平[1,2] 刘峰 张勤 韩翠 

机构地区：[1]陕西中医学院,陕西咸阳712046 [2]咸阳步长制药有限公司,陕西咸阳712000

出　　处：《辽宁中医药大学学报》2010年第6期133-134,共2页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：陕西咸阳步长制药有限公司博士后科研基金项目

摘　　要：目的:优化丹参总酮的提取工艺。方法:采用L9(34)正交试验设计,以丹参酮ⅡA和丹参总酮的含量为指标,优选丹参总酮的最佳工艺条件。结果:丹参饮片中丹参总酮的最佳提取工艺为:6倍量60%乙醇回流提取3次,0.5h/次。结论:该提取工艺设计合理,简单易行。Objective：To optimize the extracting technology of total tanshinone in Salviae miltiorrhiza.Methods ：With the content of Tanshinone ⅡA and total tanshinones as the observation index,the conditions for the extraction of total tanshinone were studied by the orthogonal experiment.Results ：the optinum extracting conditions were as follows with 6 times of 60% ethanol,each 30min,three times.Conclusion ：this procedure was convenient,appropriate and feasible.

关 键 词：正交设计 丹参 丹参酮ⅡA 总丹参酮 

分 类 号：R284.1[医药卫生—中药学]