BNP在老年多疾病所致呼吸困难中的应用研究  

Research of BNP in the old age with dyspnea caused by multi-organ disease

作　　者：肖航[1] 刘玮[2] 司良毅[1] 

机构地区：[1]第三军医大学西南医院老年病科,重庆400038 [2]第三军医大学大坪医院眼科,重庆400042

出　　处：《重庆医学》2010年第11期1384-1384,1386,共2页Chongqing medicine

摘　　要：目的探讨脑钠肽(BNP)在老年多疾病患者呼吸困难诊治中的应用价值。方法分别检测60岁以上心源性呼吸困难组及肺源性呼吸困难组患者BNP含量,并对混合性呼吸困难组患者治疗前后血浆BNP含量进行比较。结果心源性呼吸困难组患者血浆BNP含量显著高于肺源性呼吸困难组(P<0.01),对于混合性呼吸困难组患者采用强心、利尿、扩管等抗心衰治疗后,患者BNP显著下降(P<0.01),呼吸困难症状明显好转。结论 BNP在心源性因素或肺源性因素所致呼吸困难的鉴别上有重要价值。在以心源性因素主导的多疾病所致老年呼吸困难患者中,BNP含量变化与患者病情转归、心功能变化密切相关。Objective To research the value of BNP in the old with dyspnea caused by multi-organ disease.Methods Compared the BNP level of patients suffered from cardiac failure with those suffered from AECOPD.Researched the variation of BNP level of the patients suffered from multi-organ disease around the therapy.Results The BNP level of patients suffered from cardiac failure was higher than that of those suffered from AECOPD（P〈0.01）.The BNP level of the patients suffered from multi-organ disease decreased obviously by therapy.Conclusion The BNP is very important in distinguishing the reason of dyspnea caused by cardiac failure or COPD.The variation of BNP level relates with the prognosis of ill and heart function of the old with dyspnea by multi-organ disease especially by cardiac failure.

关 键 词：BNP 呼吸困难 多疾病 

分 类 号：R563.9[医药卫生—呼吸系统]