血府逐瘀汤治疗局灶性脑挫裂伤的疗效观察  

The observation on the curative efficacy of Xuefu Zhuyu Decoction in treatment for focal cerebral contusion

作　　者：林荫[1] 张国锋[1] 

机构地区：[1]福建省南平市第一医院神经外科

出　　处：《中西医结合实用临床急救》1999年第1期10-12,共3页

摘　　要：目的：观察血府逐瘀汤治疗局灶性脑挫裂伤的临床疗效。方法：将３６例无明显或轻微占位效应的外伤性局灶性脑挫裂伤患者随机分为血府逐瘀汤治疗组（１９例）和地塞米松对照组（１７例），２组均用２０％甘露醇及神经细胞活性药物作基础治疗。治疗组伤后第３日起加服中药血府逐瘀汤，每日１剂，连服２～３周；对照组加用地塞米松静滴，２周后减量停药。结果：２组在颅内压恢复正常及血性脑脊液转清方面均无显著性差异；而在临床症状缓解率，颅脑ＣＴ显示脑挫裂伤病灶修复及脑电图恢复正常方面，治疗组均明显优于对照组（Ｐ均＜０．０１）。结论：血府逐瘀汤有加速脑挫裂伤中血肿的吸收、促进神经细胞功能恢复的作用。Objective:To observe the clinically curative efficacy of Xuefu Zhuyu Decoction(血府逐瘀汤) on treatment for focal cerebral contusion.Methods:36 cases with focal cerebral confusion who had not obviously or only slightly occupied site effects were divided into Xuefu Zhuyu Decoction treatment group ( n =19) and dexamethasone group ( n =17) as control.Both groups were treated with 20% mannitol and active drugs of neuronal cell as basic therapy.On the third day after injury,Xuefu Zhuyu Decoction once a day was added for 2 or 3 weeks to treatment group,however,dexamethasone infused intravenously added and was decreasing in dose and withdrawn 2 weeks latter in control group.Results:There were no differences between two groups in recovering intracerebral pressure to normal and changing cerebrospinal fluid to transparent,but the alleviating rate of clinical symptoms,the repair of focus of cerebral contusion imaged on CT and the recovery of CCG in treatment group were significantly better than those in control group (all P <0 01).Conclusions:Xuefu Zhuyu Decoction possesses very effective actions on promoting absorption of hematoma caused by cerebral contusion and functional recovery of neuronal cells so that it is valuable to be used in treatment for cerebral contusion.

关 键 词：脑挫裂伤 局灶性 血府瘀汤 地塞米松 疗效 

分 类 号：R269.511.5[医药卫生—中西医结合] R289.5[医药卫生—中医外科学]