自杀行为候选基因5-HT2A受体基因的核酸及蛋白质分析  

Interaction among candidate genes of suicide behavior on the basis of analysis of 5-HT2AR gene and its encoded protein

作　　者：罗佳[1] 金锋[1] 

机构地区：[1]中国科学院心理研究所,北京100101

出　　处：《生物信息学》2010年第2期180-186,共7页Chinese Journal of Bioinformatics

摘　　要：为阐明自杀行为的机制,在众多的自杀候选基因中,本文着重对候选基因5-HT2Α受体基因进行了生物信息学分析,结果支持候选基因及其编码蛋白质参与自杀行为的生理生化过程,为自杀行为受基因、环境的共同作用提供了间接证据,也为自杀行为机制的后续研究奠定了基础。To provide new ideas and new tools for clarifing the mechanism of suicidal behavior. In a large number of candidate genes of suicide, this paper focuses on the bioinformatics analysis of 5-HT2A receptor gene. The data supported encoding proteins of candidate genes involving in suicide behavior in physiological and biochemical processes, provided indirect evidence for interaction of gene and environment in regulating suicide behavior and laid the foundation to clarify the mechanism of suicide behavior in the following days.

关 键 词：自杀候选基因 5-HT2ΑR 生物信息学 

分 类 号：Q94-34[生物学—植物学]