无水乙醇栓塞治疗先天性肾动静脉畸形  

Transcatheter arterial ethanol embolization for congenital renal arteriovenous malformations

作　　者：王精兵[1] 王悍[1] 安潇[1] 王麟川[1] 高礼强 周志国[1] 张贵祥[1] 

机构地区：[1]上海交通大学附属第一人民医院放射科,200080

出　　处：《介入放射学杂志》2010年第5期401-405,共5页Journal of Interventional Radiology

摘　　要：目的探讨经微导管无水乙醇动脉栓塞治疗先天性肾动静脉畸形的疗效和安全性。方法回顾性分析11例以肉眼血尿为主要症状的先天性肾动静脉畸形,选择性肾动脉造影确诊为肾动静脉畸形后,超选择性病变动脉插管,用无水乙醇栓塞病变血管治疗。结果 11例患者共进行12次治疗,无水乙醇用量5～25ml,11例肾动静脉畸形均成功栓塞,栓塞24～48h内肉眼血尿消失。术后l周内出现栓塞侧腰部酸痛、低热、腹胀、恶心、呕吐等症状,无其他严重并发症。随访4～96个月无血尿复发,肾功能正常。结论经导管无水乙醇动脉栓塞安全有效、费用低廉,是先天性肾动静脉畸形治疗的有效方法 。Objective To discuss the effect and safety of trans-microcatheter arterial embolization with ethanol for the treatment of congenital renal arteriovenous malformations. Methods Clinical data of 11 patients with congenital renal arteriovenous malformations manifested mainly as gross hematuria were retrospectively analyzed. Selective renal angiography was performed in all 11 patients. After the diagnosis was confirmed, super-selective catheterization of the diseased arteries was carried out and the trans-microcatheter arterial embolization with ethanol was conducted. Results A total of 12 procedures were completed in 11 patients. The ethanol dose used in one procedure was 5-25 ml. Successful embolization of the congenital renal arteriovenous malformations was obtained in all patients. The gross hematuria disappeared within 24-48 hours after the treatment. Lumbago at treated side, low fever, abdominal distension, nausea, vomiting, etc. occurred within one week and no other serious complications developed. During the follow-up period lasting for 4-96 months, no recurrence of hematuria was observed and the renal function remained normal. Conclusion Transcatheter arterial ethanol embolization is an economic, safe and effective treatment for congenital renal arteriovenous malformations.

关 键 词：动静脉畸形 肾 无水乙醇 栓塞 治疗性 

分 类 号：R692[医药卫生—泌尿科学]