磁共振T2＊ map成像在膝关节骨性关节炎中的应用价值  

The Application of MR T2 ＊ map Imaging in Knee Osteoarthritis

作　　者：李五根[1] 龚洪翰[1] 曾献军[1] 刘润[1] 夏国金[1] 

机构地区：[1]南昌大学第一附属医院影像科,江西南昌330006

出　　处：《实用放射学杂志》2010年第5期707-711,共5页Journal of Practical Radiology

摘　　要：目的 探讨磁共振T2＊ map成像在膝关节骨关节炎（OA）中的临床应用价值.方法 41例受检者共41个膝关节分为正常组（n=11）、轻度OA组（n=20）和重度OA组（n=10）,采用T2＊ map成像分别测量股骨内侧、外侧髁,胫骨内侧、外侧髁及髌软骨等5处软骨浅、深层T2＊值并对各组间差异进行统计学分析.正常组浅、深层之间T2＊值的比较采用独立样本t检验,正常组与轻、重度OA患者浅、深层间T2＊值的比较采用q检验.结果 正常成人关节软骨浅层T2＊值为19.9～34.0 ms,深层T2＊值为16.1～21.9 ms,两者之间存在显著性差异（P＜0.05）,轻度OA患者关节软骨浅、深层T2＊值分别为27.9～43.7 ms、23.7～31.7 ms,重度OA患者关节软骨浅、深层T2＊值分别为27.3～44.4 ms、23.8～31.5 ms,与正常组浅、深层T2＊值之间均存在显著性差异（P＜0.05）,轻度OA组与重度OA组浅、深层T2＊值之间无显著性差异（P＞0.05）.结论 MR T2＊ map成像可用于评价关节软骨生物组织构成的变化,并在早期关节软骨退变的诊断中具有一定的临床应用价值.Objective To investigate the applied value of MR T2 ＊ values in osteoarthritis （OA）of the knee. Methods A total of 41 cases was divided into 3 groups：normal group （n = 11） , mild OA group （n 20） and severe OA group （n = 10） and all cases were examined with MR T2 ＊ map. The T2＊ values of superficial and deep cartilage were measured in medial femur,lateral femur, medial tibia,lateral tibia and patellar cartilage. The T2 ＊ values were compared between superficial and deep cartilage of normal adult using independent samples t test. The T2 ＊ values of superficial and deep cartilage between the normal group and the mild and severe OA patients were compared using q test. Results The T2 ＊ values of superficial cartilage in normal adult ranged 19.9 - 34.0 ms, while the deep cartilage T2 ＊ values ranged 16.1 - 21.9 ms, there was significantly different between them（P〈0.05）. The T2 ＊ values of superficial and deep cartilage of mild OA were 27.9 - 43.7 ms, 23.7 - 31.7 ms,respectively, the T2 ＊ values of superficial and deep cartilage of severe OA were 27.3-44.4 ms, 23.8-31.5 ms. There was significant difference between the superficial and deep cartilage compared with normal group,mild OA and severe OA, however, no significance was found between mild OA and severe OA group（P〉0. 05）. Conclusion MR T2 ＊ map can be used to evaluate the articular cartilage changes in the composition of biological organization, and play an important role in the diagnosis of early cartilage degeneration.

关 键 词：膝关节 关节软骨 磁共振成像 骨关节炎 

分 类 号：R684.3[医药卫生—骨科学] R445.2[医药卫生—外科学]