2种方案防止颈椎前路手术患者呼吸道阻塞的疗效观察  

Clinical Efficacy of Two Kinds of Regimes in the Treatment of Airway Obstruction in Patients Undergoing Anterior Cervical Spine Surgery

作　　者：夏同霞[1] 周芬[1] 王玉和[1] 杨晓群[1] 蒋中艳[1] 段领燕[1] 

机构地区：[1]遵义医学院附属医院,遵义市563003

出　　处：《中国药房》2010年第22期2091-2092,共2页China Pharmacy

摘　　要：目的:探讨盐酸氨溴索雾化吸入对颈椎前路手术患者祛痰效果及呼吸道阻塞的影响。方法:62例颈椎前路手术患者术后行雾化吸入治疗,随机分为2组,每组31例。在2组基础治疗相同的情况下,治疗组雾化吸入液中加入盐酸氨溴索30mg,对照组雾化吸入液中加入α-糜蛋白酶4000IU,2组均以6～8L·min-1氧气为动力驱动喷雾器雾化吸入,每次10～15min,每日2次。2组疗程均为7d。结果:治疗组与对照组总有效率分别为97%、71%(P<0.05)。治疗组无呼吸道阻塞现象发生,对照组2例因痰液黏稠无法咳出且吸痰困难发生呼吸道阻塞而实施抢救。结论:与α-糜蛋白酶雾化吸入比较,盐酸氨溴索雾化吸入祛痰效果显著,可有效防止颈椎前路手术后呼吸道阻塞现象发生。OBJECTIVE：To probe into effect of aerosol inhalation of ambroxol hydrochloride on phlegm-removing and airway obstruction in patients undergoing anterior cervical spine surgery. METHODS：62 patients undergoing anterior cervical spine surgery were treated with primary treatment. Treatment group were additionally given 30 mg ambroxol hydrochloride added into aerosol inhalation and control group were treated with 4 000 IU α-chymotrypsin added into aerosol inhalation. Both groups were treated wreistpho innshea lraattieo nw oefr e6 ～978% L ·fomr intr-e1a tomxyengte ng-roduripv eann dae 7ro1s%ol s ftowr icceo nat rdoal yg reoaucph （timPe o0f.0 15）0～. N15o nme ionf foarir wseavye no bdsatyrus.c tRioEnS UwLaTs So：bsTehrvee tdo tianl treatment group. Two patients were practised salvage because of airway obstruction caused by dense sputum and difficulty in discharging sputum. CONCLUSION：As compared with aerosol inhalation of α-chymotrypsin,aerosol inhalation of ambroxol hydrochloride has obvious effect on phlegm-removing and prevention of airway obstruction in patients undergoing anterior cervical spine surgery.

关 键 词：盐酸氨溴索 Α-糜蛋白酶 雾化吸入 颈椎前路手术 呼吸道阻塞 

分 类 号：R969.4[医药卫生—药理学] R619[医药卫生—药学]