人内耳前庭系统膜迷路流固耦合数值模拟  

NUMERICAL SIMULATION OF MEMBRANOUS LABYRINTH IN VESTIBULAR SYSTEM OF HUMAN INNER EAR BY FLUID-STRUCTURAL INTERACTION METHOD

作　　者：沈双[1] 孙秀珍[1,2] 刘迎曦[1] 

机构地区：[1]大连理工大学工业装备结构分析国家重点实验室,大连116024 [2]大连医科大学第二临床附属医院耳鼻咽喉科,大连116025

出　　处：《力学学报》2010年第3期415-421,共7页Chinese Journal of Theoretical and Applied Mechanics

基　　金：国家自然科学基金(10872043;10902022);辽宁省自然科学基金(20082157)资助项目~~

摘　　要：基于健康志愿者右侧颞骨完整的组织切片数据,将人内耳前庭系统膜迷路内内淋巴液描述成不可压缩牛顿流体,将位于膜迷路壶腹端的平衡感受器壶腹嵴视为大变形线弹性材料,数值模拟人在立位转身、回顾时膜迷路内复杂的流固耦合作用,建立了内耳前庭系统膜迷路的三维有限元生物力学模型,分别得到不同旋转速度激励内淋巴液的压强场和壶腹嵴的位移场.研究结果有助于从生物力学的角度定量分析人在旋转时前庭膜迷路内内淋巴液和壶腹嵴相互作用的力学特性.In this paper,a three-dimensional element model of the membranous labyrinth in the vestibular system of human inner ear was reconstructed according to complete histological slides from the right temporal bones of a healthy person.The endolymph was modeled as incompressible Newtonian fluid and the crista ampullaris was represented by a linearly elastic solid undergoing large deformation.The fluid-structural interaction problem was solved with different rotation velocity excitations to simulate body turning and back looking of human.Consequently,the fluid fields of endolymph and the displacement fields of crista ampullaris for different rotation velocities were obtained respectively.The research results will contribute to quantitatively analyze the mechanical characteristics of fluid-structural interaction in the membranous labyrinth of vestibular system when human being excited by rotation velocity from the view of biomechanics,and they have provided a basis for thoroughly understanding the relationship between the anatomical structure of membranous labyrinth and the ability of human equilibrium,and for clinical diagnosis and treatment of relevant diseases of vestibular system.

关 键 词：内耳 前庭系统膜迷路 三维有限元模型 旋转速度激励 流固耦合 数值模拟 

分 类 号：R318.01[医药卫生—生物医学工程]