PLS—近红外漫反射光谱法非破坏分析磺胺脒  

NONDESTRUCTIVE ANALYSIS OF POWDER PHARMACE UTICAL SULFAGUANIDINE BY PLS NEARINF RARED DIFFUSE REFLECTANCE SPECTRA

作　　者：李玫[1] 孙莹[1] 靳丹红 任玉秋[2] 任玉林[3] 李伟[3] 郭晔[3] 

机构地区：[1]长春医学高等专科学校药学系 [2]白城卫生学校 [3]吉林大学化学系

出　　处：《计算机与应用化学》1999年第1期54-56,共3页Computers and Applied Chemistry

摘　　要：用常规和一阶导数近红外漫反射光谱法非破坏分析了粉末药品磺胺脒。比较了偏最小二乘（ＰＬＳ）法在两种情况的定量预测能力。讨论了波长间隔对ＰＬＳ预测结果的影响。未发现在运用ＰＬＳ法前进行微分处理数据所产生的明显的优点。The powder pharmaceutical samples of sulfaguanidine are analyzed nondestructive by conventional and first derivative near infrared diffuse reflectance spectra. The quantitative prediction abilities of Partial Least Squares method in both cases are compared. The influence of the wavelengths on the capacity of PLS is discussed. Significant advantages have not been found by differentiation process prior to the application of LSP method.

关 键 词：PLS法 近红外 漫反射光谱 碘胺脒 分析 

分 类 号：R978.2[医药卫生—药品]