脑出血后脑水肿药物治疗现状与展望  

Medical treatment in cerebral edema after intracerebral hemorrhage:current and prospect

作　　者：曲方[1] 周中和[1] 

机构地区：[1]沈阳军区总医院神经内科,沈阳110840

出　　处：《中国实用内科杂志》2010年第6期518-520,共3页Chinese Journal of Practical Internal Medicine

摘　　要：脑水肿是脑出血(ICH)后重要的继发性脑损伤,是病情恶化和死亡的主要原因,血凝块毒性作用是脑水肿的主要机制之一。本文介绍了常用的抗脑水肿药物包括甘露醇、甘油、高渗盐水、呋塞米、白蛋白、糖皮质激素、β-七叶皂甙钠、抑肽酶等,并展望了有希望用于ICH治疗的药物如依达拉奉、去铁敏、阿加曲班、塞来昔布。The brain edema is a secondary cerebral injury in intracerebral hemorrhage（ICH） and one of the main causes of deterioration and death. The toxic effect of blood clots is involved in the formation of brain edema. The article reviews the commonly used antiedema drugs including mannitol, glycerol, hypertonic saline, furosemide, albumin, glucocorticoids, sodium aescinate and aprotinin, and introduces such hopeful drugs as edaravone, deferoxamine, argatroban and celecoxib in the treatment of ICH.

关 键 词：脑出血 抗脑水肿 药物治疗 

分 类 号：R5[医药卫生—内科学]