新疆阿克苏农村地区慢性阻塞性肺疾病危险因素分析  

Risk factors for chronic obstructive pulmonary disease in AkeShu rural areas in Xinjiang

作　　者：荣艳[1] 凌敏[1] 胡翠芬[2] 程庆林[2] 艾尔肯.克然木 王辉[1] 赵明华[3] 韩克斯[3] 

机构地区：[1]新疆自治区人民医院呼吸二科,乌鲁木齐830001 [2]阿克苏地区第二人民医院,新疆阿克苏843000 [3]新疆自治区人民医院呼吸功能检查室,乌鲁木齐830001

出　　处：《中国实用内科杂志》2010年第6期528-530,共3页Chinese Journal of Practical Internal Medicine

基　　金：中华医学会临床医学慢性呼吸道疾病科研专项资金(07010160024)

摘　　要：目的探究新疆阿克苏地区农村慢性阻塞性肺疾病(COPD)的危险因素。方法采用整群随机抽样方法 2007年12月至2008年1月随机抽取阿克苏农村地区2887名常住人口为调查对象,进行问卷和肺功能检测。以支气管舒张试验后,FEV1/FVC<70%,并排除其他心肺疾病作为COPD的诊断标准。结果共有2568名资料完整者纳入分析,该地区农村COPD总患病率为3.9%,知晓率仅为9.9%;多因素分析显示,COPD的主要危险因素有维吾尔族(维吾尔族与汉族比较,OR=3.496,95%CI:1.986～6.156)、年龄(≥60岁与<20岁比较,OR=79.457,95%CI:10.574～597.075)、症状(14岁前经常咳嗽与无此症状者比较,OR=1.703,95%CI:1.059～2.738)、体重指数(BMI)(与正常BMI比较,OR=2.548,95%CI:1.038～6.253)、肥胖(2度肥胖与正常BMI比较,OR=7.734,95%CI:1.802～33.196)。结论该地区COPD患病与维吾尔族、年龄大、14岁前经常咳嗽、低体重指数、2度肥胖密切相关。Objective To evaluate the risk factors of chronic obstructive pulmonary disease （COPD） in the rural areas of AkeShu. Methods This is a population-based and cross-sectional survey on prevalence of COPD in the sourth of XinJiang. The data of 2887 people was collected from ten villages in three countrysides of AkeShu by cluster-random-sampling method. People were interviewed with questionnaires and tested with spirometry. The ratio of post-bronchodialators forced expired volume in one second to forced vital capacity（FEV1/FVC） × 100% 〈 70% was used as diagnostic criteria of COPD. Results Of 2568 participants with complete information,67. 2% were Uygurs and 32. 8% were Hans. Of this group,the mean age was 40. 5 ± 15.5 and average prevalence of COPD was 3.9% and awearness of COPD was 9.9%. Logistic regression model was conducted and statistical association of COPD was found with Uygurs（ Uygurs vs Hans：OR = 3.496,95% CI：I. 986 - 6. 156）, age（60 years or older vs younger than 20 ： OR = 79. 457,95% CI ： 10. 574 - 597. 075 ）, frequent cough before age 14 （ frequent coughing VS never coughing：OR = 1. 703,95% CI：I. 059 - 2. 738 ）, lower body mass index （1 ower body mass index VS normal body mass index： OR = 2. 548,95% CI ： 1. 038 ~ 6. 253 ） and second degree obesity（ second degree obesity VS normal body mass index：OR = 7. 734,95% CI：1. 802 -33. 196）. Conclusion The prevalence of COPD was related with Uygurs,age,frequent cough before age 14,low body mass index and Second degree obesity.

关 键 词：慢性阻塞性肺疾病 危险因素 流行病学 

分 类 号：R5[医药卫生—内科学]