原发性甲状腺淋巴瘤7例临床及病理分析  

Primary thyroid lymphoma:report of 7 cases and review of literature

作　　者：蔡晓频[1] 何一凡[1] 佟杰[2] 王岩[3] 龚明[4] 李光伟[1] 

机构地区：[1]北京中日友好医院内分泌科,北京100029 [2]北京中日友好医院病理科,北京100029 [3]北京中日友好医院普外科,北京100029 [4]北京中日友好医院血液科,北京100029

出　　处：《中国实用内科杂志》2010年第6期537-538,541,共3页Chinese Journal of Practical Internal Medicine

摘　　要：目的分析原发性甲状腺淋巴瘤的临床特点及预后因素。方法回顾性分析2004—2009年北京中日友好医院收治的7例原发性甲状腺淋巴瘤的临床病理资料。结果全部病例均经甲状腺手术后病理组织学确诊,6例为中老年女性。所有患者均有甲状腺结节,部分患者有压迫症状。4例病理类型为弥漫大B细胞非霍奇金淋巴瘤,3例病理类型为黏膜相关淋巴组织B细胞淋巴瘤。病理分型为黏膜相关淋巴组织B细胞淋巴瘤及年轻患者预后较好。结论中老年女性甲状腺结节的鉴别诊断中应特别注意原发性甲状腺淋巴瘤的可能性,年龄及病理分型是影响该病预后的因素。Objective To investigate the clinical characteristics of primary thyroid lymphoma （PTL） and its prognostic factors. Methods Clinical and pathological data of 7 cases diagnosed as primary thyroid lymphoma were retrospectively analyzed. Results All of the 7 patients were diagnosed on thyroidectomy and presented with thyroid nodules,of whom 6 cases were middle-aged to elderly women and some had locally oppressive symptoms. Four cases were diagnosed as diffuse large B non-Hodgkin＇s lymphoma （DLBCL） and 3 were mucosa-associated lymphoid tissue B-cell lymphoma （MALT）. Pathological subtype of mucosa-associated lymphoid tissue B-cell lymphomas and younger patients had better prognosis. Conclusion The possibility of [rFL must be kept in mind in the differential diagnosis of thyroid nodules in middle-aged to elderly women. Age and pathological subtype are important prognostic factors.

关 键 词：甲状腺 病理分型 淋巴瘤 

分 类 号：R5[医药卫生—内科学]