重症急性肾损伤可能需要更大持续性肾脏替代治疗剂量的讨论  

Severe acute renal injury in the need for greater therapeutic dose of CRRT

作　　者：孙雪峰[1] 

机构地区：[1]解放军总医院全军肾脏病研究所,北京100853

出　　处：《中国实用内科杂志》2010年第6期572-574,共3页Chinese Journal of Practical Internal Medicine

基　　金：国家自然科学基金(30871171);全军医学科研"十一五"专项基金(08Z034)

摘　　要：重症急性肾损伤的持续性肾脏替代治疗(CRRT)合理治疗剂量目前尚不清楚,但正确设置治疗剂量是CRRT成功治疗的关键环节。本文从CRRT治疗剂量设定的依据入手,分析了目前CRRT治疗剂量与疗效的循证医学证据及其存在的问题,提出重症急性肾损伤需要更大的CRRT治疗剂量,目的在于指导临床医生合理设定CRRT治疗剂量,提高重症急性肾损伤的治疗效果。The optimal intensity of continuous renal-replacement therapy in severe acute kidney injury is uncertain,but the establishment of optimal dose of CRRT is the key to successful treatment. In this paper,the basis for setting dose of CRRT starts analysis of the current CRRT dose and the efficacy of the evidence in evidence-based medicine and problems and presents the need of severe acute renal injury for greater CRRT dose. The purpose is to guide clinicians to set an optimal CRRT dose and improve the prognosis of severe acute renal injury.

关 键 词：重症急性肾损伤 持续性肾脏替代治疗 治疗剂量 

分 类 号：R5[医药卫生—内科学]