住院患者抗菌药物临床使用情况监测调查分析  

Analysis of Antibiotics Clinical Usage Monitoring Survey in Primary Hospital

作　　者：崔挺[1] 李艳丽[1] 冯端浩[1] 

机构地区：[1]中国人民解放军第309医院药剂科,北京100091

出　　处：《中国药物警戒》2010年第6期366-369,共4页Chinese Journal of Pharmacovigilance

摘　　要：目的了解2010年第一季度我院住院患者抗菌药物临床使用情况,为临床合理用药提供参考。方法调查监测当日在院全部患者的抗菌药物使用率;按25%比例随机抽取各科室住院患者的医嘱信息及电子病历,对抗菌药物使用的各项数据进行综合分析;针对抽样科室监测结果分析住院患者抗菌药物的使用情况。结果我院抗菌药物总使用率为60.88%;抗菌药物使用以单一用药为主,占47.57%;联合用药主要集中在二联,占32.04%;全院进行病原菌检查及药敏试验比率较低,仅为27.18%。抽样科室使用的抗菌药物以β-内酰胺类为主,其中头孢菌素使用频次最高;限制使用品种使用过多,使用频次过高,以移植科使用抗菌药物所占比率最高,为19.50%;病原菌检查及药敏试验率低。结论我院抗菌药物总体使用率偏高,存在不合理使用现象,须加强抗菌药物的使用管理与监测。Objective In the first quarter of 2010 hospitalized patients in clinical use of antimicrobial agents,to provide a basis for further developing intervention to promote the rational use of drugs. Methods Investigation and monitoring all that day in patients with antibiotics usage; by about 25 percent of randomly selected offices of physician information and electronic patient records,from various angles to antimicrobial drugs used by performing a comprehensive analysis of the data; for part of the date of sampling department monitoring all hospitalized patients,the survey on the use of antibiotics. Results In my hospital antibiotic overall usage is 60.88%; antibacterial drugs to monotherapy,47.57%; combined mainly concentrated in the second with 32.04%; Institute for pathogens check and drug susceptibility testing ratio is low,only 27.18%. Sampling department use of antibiotics to β-lactam,cephalosporin most high frequency; restrictions on the use of varieties use too much,too high a frequency,the proportion is too large,transplant division special use of antimicrobial agents rates highest for 19.50%; combined usage is high,mostly in the second with the primary; pathogens check and drug susceptibility testing. Conclusions In my hospital antibiotic overall usage is high,should be considered fair use,is still a need to intensify the use of antimicrobial agents in the management and supervision.

关 键 词：住院患者 抗菌药物 不合理使用 调查分析 

分 类 号：R978.1[医药卫生—药品]