阿蒂莫耶根番荔枝内酯的研究  

Annonaceous Acetogenins from Roots of Annnona atemoya Hort

作　　者：吴萍[1] 陈文森[1] 俞千[2] 吴毓林[2] 

机构地区：[1]中国科学院华南植物研究所,广州510650 [2]中国科学院上海有机化学研究所生命有机化学国家重点实验室,上海200032

出　　处：《有机化学》1999年第1期46-52,共7页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(29672036)资助项目

摘　　要：从阿蒂莫耶(Annona atemoya Hort)根中分离到一个新的含有四个羟基的邻双四氢呋喃环型番荔枝内酯(Annonaceous acetogenin)-阿蒂莫耶素C(Atemoycin C),同时分离到五个已知番荔枝内酯isocherimolin-1、bullatacin、rollinicin、almunequin和atemoyacin B。Atemoyacin C(1), a novel C - 35 tetrahydroxy adjacent bis - tetrahydrofuranyl annonaceous acetogenin was isolated from the alcoholic extracts of the roots of Armona atemoya Hort. Its structure was elucidated based on spectroscopic methods. In addition, five known acetogenins, isocherimolin - 1 (2), bullatacin (3) ,rollinicin (4) ,almnnequin (5) and atemoyacin B (6) were also isolated from the same plant.

关 键 词：番荔枝内酯 阿蒂莫耶根 阿蒂莫耶素 抗肿瘤药 

分 类 号：TQ464.1[化学工程—制药化工] R979.1[医药卫生—药品]