微波辐射下碘代芳烃与乙酰乙酸乙酯反应研究  

Microwave-assisted reaction of aryl iodo and ethyl acetoacetate

作　　者：徐绍红[1] 张伟[1] 

机构地区：[1]新乡学院化学与化工学院,河南新乡453000

出　　处：《化学研究与应用》2010年第6期782-785,共4页Chemical Research and Application

摘　　要：The C-C coupling reaction between ethyl acetoacetate and aryl iodides,catalysted by CuI,in the presence of N-methyl glycine under microwave irradiation in DMSO was studied.It afforded an efficent protocol to synthesis arylated acetoacetate ester.Microwave irradiation reduced reaction times obviously.Most interestingly,as the changing of bases and prolonging of reaction times,deacylated and decarboxy ester reaction resulted in succession.The C-C coupling reaction between ethyl acetoacetate and aryl iodides,catalysted by CuI,in the presence of N-methyl glycine under microwave irradiation in DMSO was studied.It afforded an efficent protocol to synthesis arylated acetoacetate ester.Microwave irradiation reduced reaction times obviously.Most interestingly,as the changing of bases and prolonging of reaction times,deacylated and decarboxy ester reaction resulted in succession.

关 键 词：微波 芳基乙酸酯 碘代芳烃 偶联反应 

分 类 号：O625.75[理学—有机化学]