吉非罗齐胶囊处方的优选  

OPTIMUM FORMULA OF GEMFIBROZIL CAPSULES BY ORTHOGONAL DESIGN

作　　者：黄弘彦 于富生 孙殿甲 李萍[1,2] 

机构地区：[1]新疆华世丹药业有限公司 [2]新疆医学院药学系

出　　处：《中国医药工业杂志》1999年第3期118-120,共3页Chinese Journal of Pharmaceuticals

摘　　要：通过正交试验设计，以Ｔｄ值为指标，优选出吉非罗齐胶囊的最佳处方组成为：每粒含吉非罗齐０．３ｇ，淀粉０．０１ｇ，低取代羟丙纤维素０．０１５ｇ，新配方胶囊的溶出度显著优于原产品。By orthogonal design with T d as index,the optimal formula of gemfibrozil capsules was 0.3g gemfibrozil,0.01g starch and 0.015g L HPC in every capsule. The dissolution of capsules with new formula was much better than that of the old ones.

关 键 词：吉非罗齐 正交试验 溶出度 胶囊 

分 类 号：R972.6[医药卫生—药品] R927.1[医药卫生—药学]