骨髓增生异常综合征骨髓巨核细胞的观察  

Observation of the megakaryocytes in bone marrow in myelodysplastic syndromes

作　　者：周萍[1] 唐吉斌[1] 曹春鸾[1] 胡志军[1] 崇慧峰[1] 

机构地区：[1]铜陵市人民医院临床检验中心,244009

出　　处：《安徽医学》2010年第5期504-505,共2页Anhui Medical Journal

摘　　要：目的通过对骨髓增生异常综合征(MDS)各型中骨髓病态巨核细胞的观察,探讨其在MDS诊断和分型中的作用。方法对67例MDS患者骨髓片中的巨核细胞进行分类,比较及分析。结果高危亚型组和中危亚型组各类病态巨核细胞检出率均明显高于低危亚型组(P<0.05)。结论髓象中各种病态巨核细胞检出率大小与MDS病态造血程度呈正相关性,对MDS的诊断和分型有重要意义。Objective To observe the dysmegakaryocytopoiesis（dysMK） in bone marrow in patients with Myelodysplastic Syndromes （MDS） ,and to explore the effect in diagnosing and classification in MDS. Methods 67 cases with MDS of bone marrow were classified and compared and analyzed. Results The incidence of dysMk in the RAEB group and the RCMD group were significant higher than those in RCUD or RARS group（ P 〈 0.05 ）. Conclusion The inciderce of dysMk and extent of MDS disordered present positive relative and shows a clinical signifcance in diagnosing MDS and classification in bone morrow.

关 键 词：骨髓增生异常综合征 病态巨核细胞 诊断 治疗 

分 类 号：R551.3[医药卫生—血液循环系统疾病]