一种改进型透磷灰石骨水泥的组织学实验研究  

Histological of An Improved Brushite Bone Cement

作　　者：王爱新[1] 杨洪[1] 李慧[1] 

机构地区：[1]河南师范大学生命科学学院,河南新乡453007

出　　处：《河南师范大学学报（自然科学版）》2010年第3期108-111,共4页Journal of Henan Normal University(Natural Science Edition)

基　　金：河南省自然科学基金(0411031900)

摘　　要：在β-TCP+MCPM骨水泥的基础上添加α-TCP,得到一种改进型透磷灰石骨水泥.以传统的透磷灰石骨水泥为对照组,对其做了肌内植入试验,骨内植入试验,结果表明:两种骨水泥植入肌肉后引起轻微的炎症反应,实验组引发炎症反应的程度小于对照组,4周后炎症反应均基本消失.对照组在体内的降解率大于实验组.制备的复合骨水泥克服了透磷灰石骨水泥浸泡容易溃散等缺点,并且有着比传统的透磷灰石骨水泥更好的组织学相容性.Adding α-TCP to β-TCP＋MCPM bone cement to be an improved type of brushite bone cement,the tests include intramuscular implantation test and bone implantation test,and comparing with the brushite bone cement.The results show that the two types of bone cement in muscle caused mild inflammatory response after implanting,the degree of the experimental group triggered inflammatory response is less than the control group.The inflammation nearlly disappeared after 4 weeks.The control group have more larger degradation rate than the experimental group in the body.the composite bone cement have preparated overcome the shortcomings of brushite cement,such as collapsibily easily when immersed and has the better histological compatibility comparing with brushite cement.

关 键 词：透磷灰石 组织相容性 肌内植入 骨内植入 

分 类 号：R318.08[医药卫生—生物医学工程]