紫外分光光度法测定氟吡汀的离解常数  

Determination of dissociation constant for Flupirtine by UV

作　　者：王雪彦[1] 沈怡[1] 蔡秀凤[1] 刘小玮[1] 晁若冰[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2010年第3期369-370,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的测定氟吡汀的离解常数(pKa)。方法采用UV法进行测定。结果氟吡汀的pKa值为5.52。结论所用方法快速、简便,结果准确、可靠。OBJECTIVE To determine the dissociation constant of Flupirtine.METHODS The UV spectrophotometric method was used for the determination of pKa for Flupirtine.RESULTS The pKa value of Flupirtine was 5.52.CONCLUSION This method is rapid and simple and the results are accurate and reliable.

关 键 词：氟吡汀 离解常数 紫外分光光度法 

分 类 号：R917[医药卫生—药物分析学]