阿莫西林/克拉维酸钾干混悬剂口服治疗小儿泌尿系感染临床观察  

Clinical study on amoxicillin clavulanate (7 : 1) oral suspension children with urinary tract infection.

作　　者：廖伟[1] 赵聪敏[1] 温恩懿[1] 张雨平[1] 王丽雁[1] 何周梅[1] 杨望[1] 吕奎林[1] 

机构地区：[1]第三军医大学新桥医院儿科,重庆400037

出　　处：《中国实用儿科杂志》2010年第6期475-477,共3页Chinese Journal of Practical Pediatrics

摘　　要：目的评价阿莫西林/克拉维酸钾混悬剂口服治疗小儿泌尿系感染的安全性及有效性,为临床治疗提供依据。方法将第三军医大学新桥医院2008年3月至2009年1月确诊的泌尿系感染患儿68例随机分为治疗组(35例)和对照组(33例)。治疗组给予阿莫西林/克拉维酸钾干混悬剂口服,每次14.3mg/kg,2次/d,疗程10～14d;对照组给予阿莫西林/克拉维酸钾序贯治疗,先静脉滴注,每次50mg/kg,2次/d,2～3d后换用阿莫西林/克拉维酸干混悬剂口服(用法同治疗组),总疗程10～14d。比较两组有效率及细菌清除率。结果治疗组与对照组总有效率分别为91.4%和93.9%,细菌清除率分别为81.3%和85.7%,两组比较差异无统计学意见(P均>0.05)。结论阿莫西林/克拉维酸钾干混悬剂口服治疗小儿泌尿系感染安全、有效、经济,值得推广。Objective To observe the effect of amoxicillin clavulanate oral suspension for children with urinary tract infection, so as to provide evidence for clinical treatment. Methods A total of 68 children with urinary tract infection were divided into amoxicillin clavulanate group and amoxicillin clavulanate sequential therapy group. The effect and bacteria clearance of two groups were assessed and compared. Results The efficiency rate of amoxicillin clavulanate group was 91.4%, and that of amoxicillin clavulanate sequential therapy group was 93.9%, there being no difference in two groups （P 〉 0.05） ;The Bacteria clearance rate in amoxieillin clavulanate group was 81.3%, and that in amoxicillin clavulanate sequential therapy group was 85.7%, there being no significant difference in two groups （P 〉 0.05）. Conclusion Amoxicillin clavulanate oral suspension for the children with urinary tract infection is safe, effective and economied, with is worth clinical appliation.

关 键 词：阿莫西林/克拉维酸钾 儿童 泌尿系感染 尿培养 细菌 

分 类 号：R978.1[医药卫生—药品]