慢性前列腺炎病原学的初步研究  

A preliminary study of etiology of chronic prostatitis

作　　者：邵强[1,2] 张玉海[1,2] 吕文成[1,2] 吴国荃[1,2] 马俊[1,2] 许淑珍[1,2] 张月清[1,2] 曹凌云[1,2] 

机构地区：[1]首都医科大学附属北京友谊医院泌尿外科 [2]北京市第二医院检验科

出　　处：《中华泌尿外科杂志》1999年第3期173-174,共2页Chinese Journal of Urology

摘　　要：目的对慢性前列腺炎的尸体前列腺组织标本进行病原学、病理组织学变化的研究，并对病原体与病理组织学变化的相关性进行初步探讨。方法从１９９６年５月～１９９７年１２月，对１１４例２０～４０岁慢性前列腺炎组织标本用细菌学培养、多聚酶链反应（ＰＣＲ），对组织内的沙眼衣原体、解脲脲原体、病毒、淋球菌进行检测及病理组织学检查。结果１１４例前列腺组织标本中病原体检测阳性５９例（５２％），其中单纯细菌性病原体阳性４２例，单纯沙眼衣原体（ＣＴ）６例，人类巨细胞病毒（ＣＭＶ）２例，解脲脲原体（ＵＵ）１例，人体乳头状病毒（ＨＰＶ）１例，７例为复合病原体。所有标本均存在不同程度的灶性慢性前列腺炎病理组织学变化。临床检测的病原体并不引起特异性病理组织学变化。结论慢性前列腺炎有单纯的病原体感染，还有复合感染，应予重视。慢性前列腺炎发病机制多为逆行感染。Objective To probe into the etiology and histopathology of chronic prostatitis in autopsy prostates. Methods From May 1996 to December 1997,a total of 114 autopsy prostates were studies histopathologically with detection of bacteria,chlamydia trachomatis,ureplasma urelticum,virus and neisseria gonorrhoeae by culture and PCR. Results Of the 114 prostates,a positive etiology has been detected in 59(51.8%) and negative in 55(48.2%).In the former group,the pathogen was simple bacterial in 42 (71.2%) and simple nonbacterial in 10(16.9%).The histopathological pattern was not specific for diffe rent pathogens. Conclusions Different pathogens have been found but no specific histopathological manifestations were observed for different pathogens of chronic prostatitis.

关 键 词：慢性 前列腺炎 病原学 病理组织学 

分 类 号：R697.330.3[医药卫生—泌尿科学]