盐酸氨溴索联合复方玄驹胶囊治疗精液液化异常的临床疗效观察  

Effect of the combination ambroxol hydrochloride and co-xuanju capsule in treatment of semen liquefaction

作　　者：韩明[1] 胡波勇[1] 龚仁杰[1] 邱劲[1] 姚兵[1] 朱宏刚[1] 

机构地区：[1]湖北省新华医院泌尿外科,武汉430015

出　　处：《中国医师进修杂志》2010年第17期16-18,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的 比较盐酸氨溴索联合复方玄驹胶囊口服与单用复方玄驹胶囊、盐酸氨溴索口服治疗精液液化异常的临床效果.方法 选择确诊的精液液化异常患者60例,采用随机数字表法分为三组,每组20例.A组：盐酸氨溴索（60mg口服,每日3次）＋复方玄驹胶囊（1.26 g口服,每日3次）;B组：单用复方玄驹胶囊（1.26 g口服,每日3次）;C组：单用盐酸氨溴索（60mg口服,每日3次）.共治疗3个月.分析比较治疗前后精液液化时间、精液质量的变化.结果 与治疗前比较,三组患者治疗后精液液化时间异常均有明显改善（P〈0.05）,精液质量[精子密度、精子活率、a级和（a＋b）级精子比率]亦有明显改善（P〈o.05）.治疗后A、B和c组精液液化时间〈60min的患者分别为17、11和14例,A组精液液化时间〈60min的例数明显多于B.C组（P〈0.05）,A组精液质量与B,C组比较差异均有统计学意义（P〈0.05）,而B组和C组比较差异无统计学意义（P〉0.05）.结论 应用盐酸氨溴索联合复方玄驹胶囊能显著改善精液液化时间,提高精液质量,是治疗男性不育症的一种有效方法.Objective To compare the effect of using ambroxol hydrochloride combined with co-xuanju capsule,co-xuanju capsule and ambroxol hydroehloride in the treatment of semen liquefaction.Methods Sixty semen liquefaction patients were divided randomly into three groups.Clinical trials involving 20 who received ambroxol hydrochloride＋co-xuanju capsule（group A）,20 co-xuanju capsule（group B） and 20 ambroxol hydrochloride（group C）,were carried out for 3 months.The changes of semen liquefaction time and semen quality were measured and assayed before and after treatment Results Compared withpretherapy,various parameters in the semen quality and semen liquefaction time after treatment all had a significantly difference in every group,and the patients of semen liquefaction time less than 60 minutes were 17 in group A,11 in group B and 14 in group C respectively.The results of semen liquefaction time andsemen quality in group A were significandy higher than the other groups（P〈0.05）,but the results between group B and group C had no significant difference.Conclusion The combination of ambroxol hydrochlorideand co-xuanju capsule can eridently improve the semen liquefaction time and semen quality and is an effective method in treating male infertility.

关 键 词：氨溴索 复方玄驹胶囊 精液液化 

分 类 号：R698.2[医药卫生—泌尿科学]