力竭游泳对大鼠肠组织MDA、游离巯基和ATP含量的影响  

The Effects of Exhaustive Swimming on Lipid Peroxidation,Free Thiol Group and ATP Contents in the Rat's Intestine Tissues

作　　者：常波[1] 麻新远[2] 衣雪洁[1] 

机构地区：[1]沈阳体育学院运动人体科学系,辽宁沈阳110102 [2]长春工业大学体育部,吉林长春130012

出　　处：《北京体育大学学报》2010年第5期41-43,共3页Journal of Beijing Sport University

基　　金：辽宁省教育厅科学技术研究项目(2009A670)

摘　　要：探讨力竭性运动引起的氧化应激对肠功能的影响及运动性肠功能紊乱的原因,32只SD雄性大鼠随机分为4组:即对照组(C);运动后即刻组EX;运动后30 min组(EX30);运动后60 min组(EX60),测定力竭性游泳后不同时相,肠组织匀浆MDA、游离巯基(Free-SH)和ATP含量。结果显示,运动后肠组织MDA含量在运动后30 min,60 min显著性增加(P<0.01);运动后Free-SH含量在运动后30min(P<0.05)和运动后60 min后(P<0.01)显著下降;运动后30 min组ATP含量显著下降(P<0.01)。结果提示,运动源性自由基产生增加,使得肠组织中游离巯基被氧化,导致ATP含量下降,可能是造成运动性肠功能紊乱的重要因素之一。In order to investigate the effects of oxidative stress on intestines function and the exercise-induced intestines function disorder,32 male SD rats were divided into four groups（that is control group,immediate postexercise group,30 min postexercise group and 60 min postexercise group）.The research measures the contents of MDA、FREE-SH and ATP contents in rats intestine tissues.The result shows that MDA content has significant increase at 30 min and 60 min after exhaustive swimming while FREE-SH contents has remarkable decrease in the 30 min postexercise group and 60 min postexercise group.At the same time,ATP content decline significantly 30 min postexercise group.The result suggestes that increase of exercise-induced free radicals led to FREE-SH of intestine cross-link,which resulted in the decline of ATP content.These might be important factors of exercise-induced intestine disorder.

关 键 词：力竭性游泳 丙二醛 游离巯基 ATP 肠组织 脂质过氧化 损伤 氧化磷酸化 

分 类 号：G804.7[文化科学—运动人体科学]