羊垂体前叶降钙素基因相关肽(CGRP)与P物质(SP)免疫反应神经纤维  

CALCITONIN GENE RELATED PEPTIDE(CGRP) AND SUBSTANCE P (SP) IMMUNOREACTIVE NERVE FIBERS IN ANTERIOR PITUITARY OF GOAT

作　　者：沈霞芬[1] 贾维真 卿素珠[1] 陈谊[1] 刘惠玲[2] 林英华[2] 鞠躬[2] 

机构地区：[1]西北农业大学 [2]第四军医大学神经科学研究所

出　　处：《畜牧兽医学报》1999年第2期133-138,共6页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家自然科学基金;陕西省自然科学基金

摘　　要：应用免疫组化ＡＢＣ法发现羊垂体前叶有降钙素基因相关肽免疫反应神经纤维存在，这些纤维呈串球状分布于结节部及远侧部前２／３区域。纤维形态多样，细长者穿行于腺细胞之间；短小弯曲者围绕于腺细胞周围；反复分支折叠盘曲缠绕成团簇状者将腺细胞成堆的网络其中。神经纤维及串珠与腺细胞关系密切，提示有可能对腺细胞分泌起直接支配作用。在纤维分布区域可见散在的免疫反应细胞，形态不规则，大部分与神经纤维无接触关系，但有少数可位于纤维的网络之中。Ｐ物质免疫反应神经纤维及细胞在羊垂体前叶分布稀疏，且多位于结节部，远侧部很少。Calcitonin gene related peptide immunoreactive nerve fibers in the anterior pituitary of the goat were found with ABC method of immunohistochemistry.These fibers occurred in the 2/3 front area of pars distalis and pars tuberalis,showed clear moniliform.They had many shape,the long and thin fibers passed through glandular cells;the short and winding fibers surrounded by glandular cells;the branches of them folded and rolled into a network,many cells were on it.The close relation between fibers and cells suggest that they may play a direct role in the secretion of the cells.The scatterred CGRP ir cells were observed in fibers area,showed irregular.Few cells were found to be in close proximity to nerve fibers,several cells occurred in fibers network.There were a few sp ir cells and fibers in anterior pituitary of the goat,many of them were in pars tuberalis,few in pars distalis.

关 键 词：垂体前叶 免疫组化 P物质 羊 CGRP 

分 类 号：S858.262.1[农业科学—临床兽医学] S852.165[农业科学—兽医学]