中耳炎颞骨咽鼓管峡部粘-软骨膜的组织病理学观察　  

Histopathologicly observational study of cartilage-mucosa on the eustachian tube isthmus of temporal bone with otitis media

作　　者：张全安[1] 郑国玺[1] PaparellaMM 

机构地区：[1]西安医科大学第二临床学院耳鼻咽喉科,西安710004 [2]美国明尼苏达大学中耳炎研究中心

出　　处：《临床耳鼻咽喉科杂志》1999年第4期161-163,共3页Journal of Clinical Otorhinolaryngology

基　　金：美国国际听力基金

摘　　要：了解中耳炎性病变对咽鼓管峡部粘－软骨膜的影响。方法：用光镜对３２耳各型中耳炎颞骨（中耳炎组）与５０耳正常颞骨（正常组）标本连续切片的咽鼓管峡部粘－软骨膜、中耳腔鼓岬粘骨膜进行组织病理学比较观察。结果：中耳炎组和正常组颞骨标本咽鼓管峡部均无病理性阻塞；中耳炎组峡部粘－软骨膜厚度测量和病理观察，未见有明显炎症改变，与正常组比较无明显差异；而其中耳腔粘骨膜均有明显炎性病变。这种对炎症截然不同反应的界限恰好在咽鼓管的骨与软骨交界处。结论：由于组织结构的特殊性，咽鼓管粘－软骨膜对炎症具有很强的屏障功能，极少可能受炎症影响而阻塞咽鼓管腔。Objective: To explore the influence of inflammatory pathology change of otitis media upon cartilage-mucosa at the eustachian tube isthmus (ETI). Method:The cartilage-mucosa at ETI and bone-mucosa on the tympanic promontory of 32 temporal bones with otitis media were observated histopathologiclly in comparsion with 50 normal temporal bones under light microscopy. Result:The eustachian tube isthmus in all the 32 temporal bone with otitis media and in 50 normal temporal bone were unblocked. The thick-measures and pathology observations of the cartilage-mucosa on ETI in the temporal bones with otitis media revealed there was no obviously inflammatory change and no significantly difference in comparsion with the normal control group. But there was obviously inflammatory pathologic change on the bone-mucosa of tympanic promomtory of temporal bone with otitis media. The demarcation line of completely different inflammatory reaction in middle ear cleft was exactly at the connective line between cartilage and bone of eustachian tube. Conclusion: With the specifically histologic structure, the cartilage-mucosa on eustachian tube is possessed of very strong function of natural defence for inflammatory desease, and it almost is impossible to lead to obstruction of eustachian tube by inflammatory influence upon the cartilage-mucosa.

关 键 词：中耳炎 咽鼓管峡部 颞骨 病理学 

分 类 号：R764.210.2[医药卫生—耳鼻咽喉科]