变应原体外检测系统对常年性变应性鼻炎的SlgE检测  

The examination of SIgE in perennial allergic rhinitis with Mast allergy test system

作　　者：卢迪卿[1] 李理[1] 候小清[1] 翟月明[1] 

机构地区：[1]广州医学院第二附属医院变态反应科,广州510260

出　　处：《临床耳鼻咽喉科杂志》1999年第4期166-167,共2页Journal of Clinical Otorhinolaryngology

摘　　要：探讨变应原体外检测系统（Ｍａｓｔ系统）对常年性变应性鼻炎（ＰＡＲ）检测血清特异性免疫球蛋白Ｅ（ＳＩｇＥ）与皮肤试验（皮试）、鼻粘膜激发试验（激发试验）的相关性。方法：以该系统检测５７例ＰＡＲ患者。结果：粉尘螨与屋尘螨ＳＩｇＥ阳性检出率最高（均为５２．６％），皮试和激发试验的灵敏度分别为８８．４％和８８．９％；芽枝菌属、青霉菌属和交链孢属ＳＩｇＥ阳性检出率分别为２６．３％，２４．６％和２１．０％；粉尘螨、蟑螂、虾、蟹、蛋和牛奶ＳＩｇＥ阳性检出率与变应原皮试均呈正相关（Ｐ＜０．０１），而屋尘及苋科ＳＩｇＥ与皮试无相关性（Ｐ＞０．０５）。此外，豚草ＳＩｇＥ阳性率为２２．８％，但华南地区未见豚草生长，临床应引起重视。结论：表明Ｍａｓｔ检测系统可作为ＰＡＲ致敏物的有用检测方法之一。Objective:To explore the relation between serum specificity immunoglobulin E (SIgE) and skin test (intracutaneous test) as well as nasal provocation in Perennial allergy rhinitis (PAR) by Mast Allergy Test System. Method:Serum allergen-specific IgE(SIgE) were examinated by Mast Allergy Test System in 57 case of PAR patients. Result:The SIgE positive rate of fannae and pteronvssinus are highest (52. 6% ), the sensitive rate of intracutaneous test is 88. 4% and nasal provocation is 88. 9%. The SIgE positive rates of cludosporium, penicillum and altemana are 26.3%, 24.6% and 21.0% respectively. The SIgE positive rates of fannae, cockroach, shrimp, crab, egg and milk is direct proportion with intracutaneous test (P <0.01). Pteronvssiaus and pigweek mix have no relationship with intracutaneous test (P > 0. 05). In addition, the positive rate of ragweed mix SIgE is 22. 8%, but there is non of this plant in South China. It is worthy of paying attention in clinic. Conclusion:It indicate that Mast Allergy Test System is one of the better examination for PAR allergens.

关 键 词：变应性鼻炎 SIGE 测定 鼻粘膜激发试验 

分 类 号：R765.210.4[医药卫生—耳鼻咽喉科]