东方肉穗草中酚酸类化学成分研究  

Studies on the Phenolic Acids from Sarcopyramis bodinieri var. delicata

作　　者：杨嘉永[1] 万春鹏[2] 邱彦[1,3] 

机构地区：[1]厦门大学附属第一医院,福建厦门361005 [2]江西中医学院基础医学部,江西南昌330006 [3]厦门大学医学院药学系,福建厦门361005

出　　处：《中药材》2010年第4期542-544,共3页Journal of Chinese Medicinal Materials

基　　金：福建省自然科学基金项目(2009J05088)

摘　　要：目的:研究东方肉穗草的化学成分。方法:对东方肉穗草的乙醇提取物高极性部位进行色谱层析,通过硅胶柱层析及Sephadex LH-20层析进行分离纯化,根据理化性质和波谱数据鉴定化合物结构。结果:共分离得到7个酚酸类化合物,分别为:3,3′-二甲氧基鞣花酸-4′-鼠李糖苷(Ⅰ)、鞣花酸(Ⅱ)、阿魏酸(Ⅲ)、异阿魏酸(Ⅳ)、咖啡酸(V)、3,4-二羟基苯甲酸(Ⅵ)、对羟基桂皮酸(Ⅶ)。结论:化合物Ⅰ、Ⅲ、Ⅵ、Ⅶ均为首次从该属植物中分离得到。Objective：To study the chemical constituents from Sarcopyramis bodinieri var.delicata.Methods： These compounds were isolated and purified by chromatography with silica gel column combined with Sephadex LH-20 column from high polar extracts.The structures were identified on the basis of extensive spectroscopic data analysis,and by comparison of their spectral data with those reported.Results：Seven compounds were isolated as 3,3′-di-O-methylellagic acid-4′-O-α-L-rhamnopyranoside（I）,ellagic acid（II）,ferulic acid（III）,isoferulic acid（IV）,caffeic acid（V）,3,4-di-hydroxybenzoic acid（VI）,p-hydroxycinnamic acid（VII）.Conclusion：Compound I,III,VI,VII are isolated from the genus for the first time.

关 键 词：东方肉穗草 酚酸 化学成分 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]