轻度慢性乙型肝炎患者肝组织病理特点与中医辨证分型的关系  

Relationship of Pattern Identification and Hepatic Pathology in Patients with Mild Chronic Hepatitis B

作　　者：商斌仪[1] 陈建杰[1] 高月求[1] 卓蕴慧[1] 杨婉凤[1] 孙学华[1] 朱晓骏[1] 孙岷[1] 姚军[1] 

机构地区：[1]上海中医药大学附属曙光医院肝病科,上海201203

出　　处：《上海中医药大学学报》2010年第3期46-48,共3页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：国家"十一五"科技重大专项基金资助项目(2008ZX10502)

摘　　要：目的:观察轻度慢性乙型肝炎患者肝组织病理特点与中医证型的关系。方法:在中医辨证分型的基础上,对148例轻度慢性乙型肝炎患者进行肝组织活检,检查肝组织炎症活动度(G)、纤维化程度(S)及肝细胞脂肪变性程度(F),分析比较肝组织病理特点与中医证型问的相关性。结果:瘀血阻络证患者的肝组织炎症和纤维化程度明显高于其他证型;湿热中阻证患者的肝细胞脂肪变性程度明显高于肝郁脾虚证和肝肾阴虚证。结论:患者的中医证型与其肝组织病理呈现出一定的相关性。Objective： To investigate the relationship of pattern identification and hepatic pathology in patients with mild chronic hepatitis B. Methods ： On the basis of pattern identification, 148 patients of mild chronic hepatitis B were given hepatic biopsy for grading liver＇inflammation（ G）, fibrosis（S） and fatty degeneration（F）. Then the relationship of pattern identification and hepatic pathology was analyzed. Results： The degree of G and S of obstruction of collaterals by blood stasis pattern was sig- nificantly higher than that of other patterns and the degree of F of accumulation of dampness-heat in middle-jiao pattern was signifi- cantly higher than that of liver-stagnation and spleen-deficiency pattern and liver-kidney yin deficiency pattern. Conclusion： There are some correlations between TCM patterns and hepatic pathology in patients with mild chronic hepatitis B.

关 键 词：乙型肝炎 病理 辨证分型 

分 类 号：R259[医药卫生—中西医结合]