布地奈德联合沙丁胺醇治疗小儿支气管哮喘疗效分析  

Curative effect of Budesonide combined with Salbutamol in treatment of children with bronchial asthma

作　　者：杨少锋[1] 罗旭日 林吉涛[1] 

机构地区：[1]深圳市宝安区人民医院儿科,广东省深圳518101

出　　处：《中国基层医药》2010年第12期1615-1616,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 探讨布地奈德联合硫酸沙丁胺醇雾化吸入治疗小儿支气管哮喘的疗效.方法 哮喘患儿100例,随机分为A组50例和B组50例;B组行常规治疗,A组在常规治疗基础上加布地奈德联合硫酸沙丁胺醇雾化吸入,每天2次,疗程10 d;观察两组疗效、临床症状评分、临床表现恢复时间和不良反应.结果 A组总有效率94.0%明显高于B组的72.0%（P〈0.05）;两组治疗后患儿呼吸困难、咳嗽、喘息、哮鸣音和睡眠满意度较治疗前明显下降（均P〈0.01）;A组呼吸困难、咳嗽、哮鸣音的恢复时间和治疗天数均少于B组（均P〈0.05）.结论 布地奈德联合硫酸沙丁胺醇雾化吸入治疗支气管哮喘有良好疗效.Objective To investigate the effect of Budesonide combined with Salbutamol in treatment of chil-dren with bronchial asthma.Methods 100 cases of children with asthma were randomly divided into conventional therapy group（Group A）50 cases and combined treatment group（Group B）50 cases;Conventional therapy was given to group B and Group A Was givend the conventional therapy puls Budesonide combined with salbutamol treatment,2 times a day.The course of treatment was 10d;The effect of clinical symptom score、clinical recovery and adverse reac-tions in two groups were observed.Results The total efficiency of 47 cases（94.O%） in group A were significantly higher than the B group 36 cases（72.0%）（P〈0.05）;The index of breathing diffculties、coushing、wheezing、wheezing sustain and sleep satisfaction after treatment were significantly decreased compared with before treatment in two groups（all P〈0.01）;The time of recovery of breath shortness、cough、asthma、wheezing and therapy hys in group A were less than group B（all P〈0.05）.Condusion Atomizing inhalation treatment of Bedesonide combined with Sallbutamol was effective to treat children with bronchial asthma.

关 键 词：布地奈德 沙丁胺醇 雾化吸入 支气管哮喘 

分 类 号：R72[医药卫生—儿科]