哺乳动物繁殖季节性相关基因的研究进展  

Advances on Related Genes with Reproductive Seasonality in Mammals

作　　者：储明星[1] 冯涛[1] 王西筠 张新珍[2] 刘雪云[2] 乔念民 郭志勇[2] 刘新朋[2] 

机构地区：[1]中国农业科学院北京畜牧兽医研究所,农业部畜禽遗传资源与利用重点开放实验室,北京100193 [2]山东省嘉祥县畜牧局,嘉祥272400

出　　处：《中国畜牧兽医》2010年第6期107-110,共4页China Animal Husbandry & Veterinary Medicine

基　　金：国家高技术研究发展计划(863)(2006AA10Z139);国家现代农业产业技术体系建设专项资金(农科教发[2008]10号);国家重点基础研究发展计划(973)(2006CB102105);国家自然科学基金项目(30871773);中国农业科学院北京畜牧兽医研究所基本科研业务费专项(2010jc-9),中国农业科学院首批优秀科技创新团队专项资助

摘　　要：光照周期或季节更替调控松果体褪黑激素的分泌,下丘脑-垂体-性腺轴接收来自褪黑激素的信息并整合机体内部生理状态后调控下丘脑GnRH的脉冲释放,确保动物在一年中最适宜的时间进行繁殖。哺乳动物在长期进化过程中形成了一定的繁殖节律,已确定一些基因与繁殖的季节性有关。笔者简要介绍了褪黑激素受体1A基因、褪黑激素受体1B基因、KiSS-1/GPR54基因等与哺乳动物繁殖季节性的关系。In mammals,the melatonin secreted by pineal gland was modulated according to the photoperiod and season.The hypothalamic-pituitary-gonadal axis accepted the messages from melatonin and integrated both external and internal status and appropriately altered the activity of the GnRH.All these supported mammals to maximize reproductive success and avoid breeding during inappropriate conditions.Reproductive rhythm was formed and fixed in the process of long evolution in mammals and some genes were identified to be related with reproductive seasonality.This review briefly introduced the relationships between MTNR1A,MTNR1B and KiSS-1/GPR54 genes and reproductive seasonality in mammals.

关 键 词：繁殖季节性 基因 多态性 

分 类 号：S814.8[农业科学—畜牧学]