应用速度向量成像技术诊断猪心肌挫伤的实验研究  

Experimental study of Applying Velocity Vector Imaging in Pigs with Myocardial Contusion

作　　者：王小燕[1] 王莎莎[1] 李叶阔[1] 朱贤胜[1] 程琦[1] 罗国新[1] 

机构地区：[1]解放军广州军区广州总医院超声影像科,广州市510010

出　　处：《中国超声医学杂志》2010年第6期493-496,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨速度向量成像(VVI)技术诊断心肌挫伤(MC)的临床应用价值。方法采用小型撞击器建立8只猪MC模型。分别于撞击前及撞击后0.5、2、4、8 h行二维超声心动图(2DE)和VVI检查,并与大体病理氯化三苯基四氮唑(TTC)心肌染色结果进行对照分析。结果撞击后损伤心肌2DE显示节段性室壁运动异常,VVI显示向量长度和方向不一致,色带变形。128节段中经大体病理证实56节段受损,撞击后0.5、2、4、8 h二者诊断MC的敏感性比较差异无统计学意义(P>0.05);伤后2、4、8 h VVI诊断MC的特异性均高于2DE,二者比较差异有统计学意义(P<0.05)。经受试者工作曲线(ROC)分析显示各时段MC节段的VVI曲线下面积均大于2DE,且伤后2、4、8 h二者比较差异有统计学意义(P<0.05)。结论 VVI检测可提高MC的诊断能力,有望成为无创评价MC的新方法。Objective To investigate the role of velocity vector imaging （VVI） in the clinical applications of myocardial contusion （MC） . Methods Eight pigs were selected and wounded to he with MC by a small striker. 0.5, 2, 4, 8 h after MC, VVI and two-dimensional echocardiography （2DE） were used, results of which were finally compared with general pathological staining and （Triphenyl tetrazolium chloride, TTC） staining. Results After MC, 2DE showed segmental wall motion abnormalities, VVI displayed disagreement of vector length and direction, the ribbon deformed. It showed that 56 segments were injured in 128 segments by general pathological staining. 8 h after impaction there was no statistic significance in sensitivity between VVI and 2DE （P〉0.05） . But specificity of VVI was higher than that of 2DE, so there was statistic significance between them （P〈0.05） . By ROC, VVI showed bigger area within each segment. There was statistic significance 8 h after the injury （P〈0.05） . Conclusions VVI can improve the diagnosis ability of MC, expected to become the new method in diagnosing MC.

关 键 词：超声心动图 速度向量成像 心肌挫伤 动物实验 

分 类 号：R540.45[医药卫生—心血管疾病] R542.2[医药卫生—内科学]