CDFI观察鼻咽癌放化疗中颈部转移性淋巴结的血供变化与近期疗效的关系  

Relation of Blood Flow Changes of Metastatic Cervical Lymph Nodes and Short-term Effect of Chemoradio- therapy Monitoring by CDFI in Nasopharyngeal Carcinoma

作　　者：符仪媚[1] 廖锦堂[1] 刘斌[2] 

机构地区：[1]中南大学湘雅医院超声影像科,长沙市410008 [2]中南大学湘雅医院放疗科,长沙市410008

出　　处：《中国超声医学杂志》2010年第6期507-510,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的了解鼻咽癌颈部转移性淋巴结放化疗中的血供变化与近期疗效的关系。方法对我院病理证实的鼻咽癌初治患者25例,共观察其颈部转移性淋巴结43枚,于化疗后、放疗10次、20次及放疗结束时连续监测转移淋巴结的彩色多普勒血流信号、血供变化及退缩情况。结果治疗前淋巴结血流分级多以Ⅱ～Ⅲ级为主,放疗结束时多为0～Ⅰ级,RI由治疗前0.711±0.142下降为0.440±0.272,放疗10次时血流减少组淋巴结退缩率明显高于血流改善组及血流无明显变化组(P<0.05)。结论彩色多普勒超声对鼻咽癌颈部转移性淋巴结治疗中血供变化的监测,有可能作为初步预测近期放化疗效果的指标之一。Objective To probe the relation between the changes of blood supply and short-term effect of chemoradiotherapy. Methods 25 patients confirmed as nasopharyngeal poorly differentiated squamous-cell carcinoma pathologically by biopsy were included, and their 43 metastatic cervical lymph nodes were examined by color Doppler flow imaging repeatedly after chemotherapy and approximately every 2 weeks during radiotherapy. Results Before treatment, Color Doppler flow signals were scored as Ⅱ-Ⅲ in most nodes. End of radiotherapy, the blood supply decreased as 0n Ⅰ and the mean RI was 0. 4404-0. 272 （ 0. 711±0. 142 before treatment） . The regression rate in the blood-flow-decreasing group was bigger than that in the blood-flow-increasing group and the same-blood-supply group. Conclusions Color Doppler flow imaging may play a role in the evaluation of nodal short-term response to chemoradiotherapy, by monitoring the changes of blood flow follow-up during therapy period.

关 键 词：鼻咽癌 颈部转移性淋巴结 彩色多普勒 血供变化 近期疗效 

分 类 号：R445.1[医药卫生—影像医学与核医学] R739.63[医药卫生—诊断学]