彩色多普勒超声在糖尿病颈动脉硬化中的应用  

Application of color Doppler ultrasonography in diabetic carotid sclerosis:report of 68 cases

作　　者：肖蓉[1] 殷军[2] 

机构地区：[1]重庆市涪陵中心医院内分泌科,重庆涪陵408000 [2]重庆市涪陵中心医院超声科,重庆涪陵408000

出　　处：《第三军医大学学报》2010年第11期1232-1234,共3页Journal of Third Military Medical University

摘　　要：目的分析彩色多普勒超声在糖尿病颈动脉硬化诊断中的应用价值,并探讨糖尿病与颈动脉硬化的关系。方法对本院诊断明确的2型糖尿病住院患者68例(观察组)、健康体检者73例(对照组)进行颈动脉超声对比分析。结果观察组颈动脉内-中膜厚度(intima-media thickness,IMT)较对照组明显增厚(P<0.01),且观察组斑块发生率较对照组明显增高(82.35%vs23.28%,P<0.01);观察组年龄小于60岁者颈动脉粥样硬化的发病率明显低于年龄超过60岁者(18.75%vs76.92%,P<0.01);血流动力学改变在中度和重度狭窄时明显,血流速度明显增快,血流量明显减低,表现为频谱充填、峰值与舒张末期流速加快,PI、RI均增高,观察组明显高于对照组(P<0.01)。结论应用彩色多普勒超声能准确检测颈动脉粥样硬化斑块的范围、性质和血管病变的程度,是评价颈动脉粥样硬化受损的手段之一。Objective To analyze the application of color Doppler ultrasonography in diagnosis of diabetic carotid sclerosis and to study the relation between diabetes and carotid sclerosis. Methods Color Doppler ultrasound findings in 68 hospitalized type 2 diabetes patients （ as an observation group） and in 73 healthy individuals （ as a control group） were compared and analyzed from Feb. 2007 to Feb. 2009. Results The tunica intima and media of carotid were significantly thicker in observation group than in control group （ P 0. 01）. The incidence rate of plaques was significantly higher in observation group than in control group （ 82. 35% vs 23. 28%,P 0. 01） while that of carotid sclerosis was obviously lower in patients （ age 60） than in those （ age≥60） of observation group （ 18. 75% vs 76. 92% ,P 0. 01）. The change in haemodynamics was more obvious in patients with mild and severe stenosis,the blood flow was rapider,the volume of blood flow was lower which was manifested as frequent filling,increased flow rate in terminal diastolic phase,and increased PI and RI,in observation group than in control group（ P 0. 01）. Conclusion Color Doppler ultrasonography can accurately detect the plaques,nature and vascular lesion of carotid sclerosis.

关 键 词：糖尿病 颈动脉粥样硬化 彩色多普勒超声 内-中膜厚度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.106[医药卫生—诊断学]