高血压前期人群血压转归及其影响因素  被引量:63

Prevalence of prehypertension and associated cardiovascular risk: two years follow up results

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作  者:吴寿岭[1] 张子强[2] 宋胜斌 么太成 李云[3] 王剑利[2] 王娜[2] 金成[2] 李金锋[2] 

机构地区:[1]华北煤炭医学院附属开滦医院心内科,唐山063000 [2]华北煤炭医学院研究生院 [3]华北煤炭医学院预防医学系 [4]开滦范各庄医院心内科 [5]开滦钱营医院心内科

出  处:《中华心血管病杂志》2010年第5期415-419,共5页Chinese Journal of Cardiology

摘  要:目的 探讨高血压前期人群血压转归及其影响因素.方法 选择2006-2007年度开滦集团公司职工健康体检中符合JNC-7高血压前期诊断标准的高血压前期人群作为观察队列.于2008-2009年度对观察队列进行第2次健康体检,观察其血压转归情况及其影响因素.结果 (1)纳入最终观察队列的高血压前期者为25 474例,第2次体检时有8361例进展至高血压.男性与女性人群进展至高血压的比例分别为35.3%、23.3%;基线血压水平在120-129/80~84 mm Hg(1 mm Hg=0.133 kPa)、130~139/85~89 mm Hg范围内的人群进展至高血压的比例分别为27.2%、43.8%;有、无危险因素的人群进展至高血压的比例分别为34.3%、19.9%.(2)多因素logistic回归分析影响进展至高血压的危险因素依次是基线收缩压、腰围、年龄、体质指数(BMI)、性别(男性)、舒张压、总胆固醇、空腹血糖、甘油三酯、低密度脂蛋白胆固醇,上述因素每增加一个单位进展至高血压的RR(95%可信区间)分别为1.052(1.048~1.056)、1.009(1.006~1.013)、1.023(1.021~1.026)、1.063(1.052~1.074)、1.554(1.442~1.675)、1.036(1.029~1.043)、1.064(1.037~1.093)、1.043(1.024~1.062)、1.041(1.021~1.062)、1.035(1.000~1.072).结论 2年间有32.8%的高血压前期人群进展至高血压.基线收缩压、腰围、年龄、BMI、性别(男性)、舒张压、总胆固醇、空腹血糖、甘油三酯、低密度脂蛋白胆固醇是进展至高血压的危险因素.Objective To observe the prevalence, blood pressure change in prehypertensive population and associated cardiovascular risk factors. Methods Data from a prehypertensive cohort defined with the JNC-7 prehypertension diagnostic criteria were obtained in the employees of kailuan group during the health examination between 2006 to 2007 and the same population was revisited between 2008 to 2009 to observe the change of blood pressure and the associated determinants for blood pressure change. Results (1) There were 25 474 prehypertensives during the 1st visit and 8361 subjects developed hypertension during the 2nd visit (35. 3% in men and 23. 3% in women, 27. 2% with baseline blood pressure 120-129/80-84 mm Hg( 1 mm Hg =0. 133 kPa) and 43. 8% with baseline blood pressure 130-139/85-89 mm Hg, 34. 3% with risk factors and 19. 9% without risk factors). (2) Multiple logistic regression analysis showed that the baseline SBP, waist circumference, age, BMI, gender (male), DBP, TC, FBG, TG, LDL-C were the risk factors of blood pressure progression with a RR (95% CI) of 1. 052(1. 048-1. 056), 1.009(1.006-1.013), 1.023(1.021-1.026), 1.063(1.052-1.074), 1.554(1.442-1.675), 1.036(1.029-1.043), 1.064 (1.037-1.093), 1.043 (1.024-1.062), 1.041 (1.021-1.062) and 1.035 (1.000-1.072), respectively. Conclusion A third (32. 8% ) prehypertensive population progressed into hypertension after two years, baseline SBP, waist circumference, age, BMI, gender (male), DBP, TC, FBG, TG, LDL-C were the risk factors of predicting blood pressure progression.

关 键 词:高血压 危险因素 随访研究 

分 类 号:R544.1[医药卫生—心血管疾病]

 

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