^(18)F-FDG PET/CT评价纵隔淋巴结老年性非特异性高摄取的价值  

Evaluation of non specific high uptake of aged mediastinal lymph nodes by ^(18)F-FDG PET/CT

作　　者：凌春香[1] 黄召勤[1] 芮军[1] 刘庆伟[1] 

机构地区：[1]山东大学附属省立医院医学影像科,济南250021

出　　处：《山东大学学报（医学版）》2010年第5期116-120,共5页Journal of Shandong University:Health Sciences

摘　　要：目的通过对纵隔淋巴结18F-FDG PET/CT表现的对比分析,探讨纵隔淋巴结老年性非特异性高摄取的PET/CT特点及其与恶性肿瘤(尤其是肺癌)纵隔淋巴结转移的鉴别。方法回顾性分析有完整临床资料的110例病例,其中老年性非特异性高摄取组55例(组1),转移组53例(组2),两组并存者2例。盲法测量PET/CT图像上高摄取淋巴结的SUVmax和SUVmean、CT图像上淋巴结的长、短径和CT值(平均值和最大值)。结果两组数据的SUV max[(3.98±1.48)mm和(7.41±3.69)mm]、SUV mean[(3.37±1.16)mm和(5.88±2.64)mm]、长径[(10.32±3.01)mm和(16.0±5.97)mm]、短径[(7.48±2.29)mm和(11.95±4.78)mm]、平均CT值[(64.16±21.73)Hu和(33.84±8.80)Hu]和最大CT值[(111.02±149.41)Hu和(67.93±32.45)Hu]差异有统计学意义(P<0.01);组1的SUV值及长短径均小于组2,而前者CT值大于后者。结论纵隔淋巴结老年性非特异性高摄取的特点为:多对称分布,SUV值多<5,CT值多>50Hu。SUV值及CT值对于淋巴结良恶性的鉴别有一定的意义,尤其是CT值增高对其与恶性肿瘤,特别是肺癌所致的淋巴结转移的鉴别有重要价值。Objective To investigate the difference of 18F-FDG PET/CT between non-specific high uptake of the aged mediastinal lymph nodes and mediastinal lymph nodes metastases caused by malignant tumors especially lung cancer.Methods 110 patients with detailed clinical data were retrospectively studied,including 55 with non specific high uptake of aged mediastinal lymph nodes（group1）,53 with mediastinal lymph nodes metastases（group2）,and 2 with both non-specific high uptake of aged mediastinal lymph node and mediastinal lymph node metastases.The SUVmax,SUVmean,length diameter,short diameter,mean CT value and maximum CT value of the lymph nodes were measured with a blind method.Results Obvious differences between group 1 and the group 2 were found in SUVmax（3.98±1.48 vs 7.41±3.69）,SUVmean（3.37±1.16 vs 5.88±2.64）,length diameter[（10.32±3.01）mm vs（16.0±5.97 mm）],short diameter[（7.48±2.29）mm vs（11.95±4.78）mm],mean CT value[（64.16±21.73）Hu vs（33.84±8.80）Hu] and maximum CT value [（111.02±149.41）Hu vs（67.93±32.45Hu）]（P0.01）.Conclusions The non-specific high uptake of aged mediastinal lymph nodes is usually accompanied with symmetrical distribution,SUV value lower than 5 and CT value higher than 50 Hu.The SUV value and CT value（particularly the increased CT value）could be used as references in the differential diagnosis of benign and malignant lymph nodes caused by malignant tumors especially lung cancer.

关 键 词：淋巴结 非特异性摄取 体层摄影术 发射型计算机 

分 类 号：R445.1[医药卫生—影像医学与核医学] R730.55[医药卫生—诊断学]