酸枣仁颗粒中酸枣仁醇提工艺条件的优选  

Optimization of Ethanol-Extracting Process of Semen Ziziphi Spinosae in Suanzaoren Granules

作　　者：夏苗芬[1] 史志超[1] 

机构地区：[1]浙江医药高等专科学校,浙江宁波315100

出　　处：《中国中医药信息杂志》2010年第6期58-59,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的研究酸枣仁颗粒的制备工艺,优选酸枣仁乙醇提取最佳工艺条件。方法以酸枣仁皂苷A提取率为指标,采用高效液相色谱法测定含量。应用正交试验设计进行筛选。结果醇提的最佳工艺条件为第1次加8倍量的70%的乙醇回流提取60min,第2次加6倍量的70%的乙醇回流提取40min,第3次加6倍量的70%的乙醇回流提取40min。结论优选得到的工艺稳定可行。Objective To study the optimum process for Suanzaoren granules, and to optimize the ethanol-extracting process for jujuboside A in Semen Ziziphi Spinosae. Methods With the extracting rate of jujuboside A as the index, HPLC was used to determine the content ofjujuboside A in extracted solution and the extracting conditions were optimized by orthogonal design. Results The optimum extracting condition was adding 8 times amount of 70% ethanol and refluxing for 60 rain, then adding 6 times amount of 70% ethanol, refluxing and extracting for 40 min （two times）. Conclusion The optimized process is stable and highly efficient.

关 键 词：酸枣仁颗粒 酸枣仁 酸枣仁皂苷A 醇提工艺 

分 类 号：R283.5[医药卫生—中药学]