重症监护病房院内感染病原菌监测及耐药性分析  

Surveillance of pathogens from patients with hospital infection and analysis of drug resistance in intensive care unit

作　　者：王磊[1] 尉玉杰[1] 井慎[1] 高静[1] 成维鹏 

机构地区：[1]安徽省宿州市皖北煤电总医院SICU,安徽宿州234000

出　　处：《华北煤炭医学院学报》2010年第1期5-6,共2页Journal of North China Coal Medical College

摘　　要：①目的了解综合性ICU获得性感染的流行病学及细菌耐药性情况,为临床防治提供依据。②方法对本院ICU所有分离的细菌菌株、真菌菌株及细菌耐药性进行回顾性调查。③结果医院获得性感染中仍以G-菌为主占69.7%,其次为真菌19.4%、G+菌10.9%。在细菌感染中,G-菌占86.5%,G+菌占13.5%。G-菌仍以铜绿假单胞菌为主,占21.7%。G+菌以金黄色葡萄球菌(金葡菌)为主33.3%。耐药性方面,细菌耐药性严重,真菌耐药性较轻。④结论细菌对常用抗生素的耐药严重,且呈多重耐药。应严格掌握抗生素使用原则,根据药敏选用抗生素。Objective To search for the prevalence of nosocomial infection and the change of drug resistance in a comprehensive intensive care unit（ICU） and provide the basis for clinical prevention and treatment.Methods The strains of bacteria and fungi were isolated from ICU and their drug resistance were retrospectively analysed.Results The main pathogen of nosocomial infection was Gram-negative bacteria（69.7%）,fungi（19.4%）and Gram-positive bacteria（10.9%） in turn.In bacterial infection,Gram-negative and G-positive bacteria were 86.5% and 13.5% respectively.In Gram-negative bacteria,pseudomonas aeruginosa was the major one（21.7%）,and in Gram-positive bacteria staphylococcus aureus（33.3%） was most prominent.Drug resistance of bacteria was severe,while which of fungi was mild.Conclusion Drug resistance of bacteria was severe and multi-drug resistance in common use antibiotics.The principle of antibiotics apply should be mastered and antibiotics was chose according to drug-sensitivity tests.

关 键 词：ICU 病原菌监测 院内感染 耐药 

分 类 号：R466.5[医药卫生—临床医学]