基于微流控芯片的酶及其抑制剂的研究进展  

Advances on enzymes and enzyme inhibitors research based on microfluidic devices

作　　者：侯凤华[1] 叶剑清[1] 陈缵光[1] 成志毅[1] 

机构地区：[1]中山大学药学院,广东广州510006

出　　处：《药学学报》2010年第6期694-698,共5页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金资助项目(20875105)

摘　　要：近20年来,随着微流控芯片加工技术的不断发展,微流控分析已从一个概念发展为当前世界上最前沿的科技领域之一,微流控芯片上酶及其抑制剂的研究也取得重要进展。微流控技术用于酶及其抑制剂研究时在减少试剂用量、缩短分析时间、自动化等方面提高了分析性能。本文综述了微流控芯片上酶及其抑制剂的研究。With the continuous development in microfluidic fabrication technology,microfluidic analysis has evolved from a concept to one of research frontiers in last twenty years.The research of enzymes and enzyme inhibitors based on microfluidic devices has also made great progress.Microfluidic technology improved greatly the analytical performance of the research of enzymes and enzyme inhibitors by reducing the consumption of reagents,decreasing the analysis time,and developing automation.This review focuses on the development and classification of enzymes and enzyme inhibitors research based on microfluidic devices.

关 键 词：酶 酶抑制剂 微流控芯片 

分 类 号：Q523[生物学—生物化学]