超声心动图定量评估先天性心脏病患者肺血流量的研究  

Quantitative assessment of pulmonary blood flow by echocardiography in patients with congenital heart defect

作　　者：徐峥嵘[1,2] 黄新胜 黄奕高[3,4] 黄涛 黄文辉[3,4] 张曹进 申俊君[3,4] 

机构地区：[1]深圳市宝安区人民医院 [2]南方医科大学附属宝安医院心内科,广东深圳518101 [3]南方医科大学附属华南医院 [4]广东省人民医院广东省心血管病研究所心内科,广东广州510080

出　　处：《南方医科大学学报》2010年第5期1163-1164,1168,共3页Journal of Southern Medical University

摘　　要：目的探索超声心动图定量评估先天性心脏病患者(CHD)肺血流量的方法 ,寻求无创性定量评估肺血流的途径。方法选择左向右分流的房间隔缺损病人64例,在超声心动图的四腔心切面下,探查右侧上、下肺静脉,记录其血流频谱,并根据当时的心率对其进行校正,计算出右上肺静脉血流速度时间积分(VTIrupv)、右下肺静脉血流速度时间积分(VTIrlpv);并与右心导管术Fick法计算出肺循环血流量(Qp)进行比较。结果经胸超声心动图所得出的右肺静脉血流速度时间积分与右心导管术计算的Qp相关性良好。结论通过超声心动图测量肺静脉血流频谱可一定程度上反映CHD患者肺血流量,其作为无创性定量评估肺血流量的检查技术可能具有潜在的应用前景。Objective To explore the possibility and reliability of echocardiography in quantitative evaluation of pulmonary blood flow in patients with congenital heart disease （CHD）. Methods Sixty-four patients with left to right shunt congenital atrial septal defect （ASD） underwent echocardiographic examinations of the right upper and lower pulmonary vein blood flow spectrum in the four-chamber face, and the right upper pulmonary vein flow velocity time integral （VTIrupv） and right inferior pulmonary venous flow velocity time integral （VTIrlpv） were calculated according to the heart rate. The VTIrupv and VTIrlpv were compared with the pulmonary blood flow （Qp） calculated by Fick method with right heart catheterization. Results There was a high correlation between the right lung vein flow velocity time integral measured by the catheter of transthoracic echocardiography and Qp. Conclusion The pulmonary venous flow spectrum measured by echocardiography can be informative of the pulmonary blood flow in patients with CHD. Echocardiography may serve as a potential noninvasive technique to evaluate pulmonary blood flow in these patients.

关 键 词：超声心动图 先天性心脏病 肺血流量 

分 类 号：R445.1[医药卫生—影像医学与核医学] R541.1[医药卫生—诊断学]