双源CT双能扫描测量骨密度的实验研究  

An experimental study of dual source CT approach measuring bone mineral density

作　　者：蒋宝国[1] 李松柏[1] 陈晓朝[2] 宣扬[2] 鲍楠[2] 康彦[2] 卑贵光[1] 李响[1] 

机构地区：[1]中国医科大学附属第一医院放射科,辽宁沈阳110001 [2]东北大学中荷生物医学与信息工程学院,辽宁沈阳110004

出　　处：《中国临床医学影像杂志》2010年第6期405-408,共4页Journal of China Clinic Medical Imaging

摘　　要：目的:评价双源CT(DSCT)双能骨密度测量方法的准确性。方法:自行设计开发的DSCT双能CT定量法(DEQCT)骨密度测量软件,与临床上广泛应用的双能骨密度测量仪(DEXA)及理论单能定量CT测量法(SEQCT)骨密度测量方法分别测定猪腰脊椎骨骨密度,并将测量值同猪脊骨煅烧后的骨密度值进行比较,观察哪种测量方法更准确。结果:DEQCT方法测量值[(0.5023±0.0353)g/cm^3]最为接近煅烧值[(0.5050±0.0434)g/cm^3],两者间差别不具有统计学意义,理论SEQCT_140kV方法测量值[(0.4813±0.0314)g/cm^3]小于煅烧值及双能测量值,两两间的差别均具有统计学差别。DEXA所测量值[(0.4527±0.0360)g/cm^2]明显小于煅烧值及DEQCT和理论SEQCT_140kV法测量值,且与三者的差别均存在统计学意义。结论:DSCT双能骨密度测量方法优于临床应用的SEQCT骨密度测量方法及DEXA测量法。Objective： To evaluate the accuracy of DEQCT in determining bone mineral density （BMD） by using dual source CT （DSCT）. Methods： BMD of the lumbar vertebral body of pig was measured by our designing software, DEQCT, at DSCT and by SEQCT software of the Neusoft and DEXA. The lumbar body of pig was then calcined, the lime of the calcined material was measured. The measuring results of DEQCT, SEQCT_（140kV） and DEXA were compared. Results： The BMD of the vertebral body and the calcined material measured by DEQCT was （0.5050 ±0.0434）g/cm^3, and （0.5023 ±0.0353）g/cm^3 respectively, there was no significant difference（P=0.779）. BMD measured by SEQCT_（140kV）[（0.4813±0.0314）g/cm^3] was significantly lower than the measurement of the calcined material. BMD determined by DEXA[（0.4527±0.0360）g/cm^2] was significantly lower than the measurement of calcined material and also significantly lower than the results measured by DEQCT and SEQCT （P〈0.05）. Conclusion： BMD determined by DEQCT at DSCT is superior to SEQCT and DEXA approach.

关 键 词：骨密度 体层摄影术 X线计算机 

分 类 号：R336[医药卫生—人体生理学] R814.42[医药卫生—基础医学]