血必净注射液治疗严重烧伤合并内毒素血症的临床疗效观察  

Clinical study on the effect of XueBiJing injection on patients with severe burn and endotoxin

作　　者：周国富[1] 向小燕[1] 吕志敏[1] 任红丽[1] 王珺[1] 

机构地区：[1]川北医学院附属医院烧伤整形科,四川南充637000

出　　处：《重庆医学》2010年第12期1525-1526,共2页Chongqing medicine

摘　　要：目的探讨血必净注射液对严重烧伤合并内毒素血症患者的治疗效果。方法将32例严重烧伤且内毒素检测阳性的患者,随机分为对照组和治疗组各16例,两组均给予抗休克补液、抗感染、营养支持以及创面处理等常规治疗,治疗组还使用血必净注射液100mL/d加入100mL生理盐水中静脉滴注,疗程7d。治疗前后分别观察两组患者血清中内毒素的含量、患者的体温(T)、心率(HR)、呼吸频率(RR)、血中白细胞计数(WBC)指标。结果治疗组治疗后各项监测指标改善情况明显优于对照组(P<0.05或P<0.01)。结论血必净对于严重烧伤合并内毒素血症的患者有明显疗效,对严重烧伤患者起到保护重要组织作用。Objective To evaluate the effects of XueBiJing injection on patients with severe burns and endotoxin.Methods 32 patients were randomly divided into treatment group（n=16） and control group（n=16）.Both groups of patients were given routine treatments,while the treatment group were given XueBiJing injection in addition.Temperature（T）,heart rate （HR）,respiration rate（RR）,white blood cell（WBC） and serum endotoxin level were observed.Results T,RR,HR,WBC and serum endotoxin level were reduced significantly in the treatment group compared with those of the control group（P0.05或P0.01）.Conclusion XueBiJing injection is effective to patients with severe burn and endotoxin.

关 键 词：内毒素血症 血必净注射液 烧伤 

分 类 号：R644.05[医药卫生—外科学]