心磁图在冠心病诊断中的临床应用  

The clinical application of magnetocardiography in diagnosis of coronary heart disease

作　　者：赵丹[1] 陈元禄[1] 刘芳[1] 王建勇[1] 赵春玲[1] 陈庆华[1] 

机构地区：[1]天津医科大学心血管病临床学院,天津300457

出　　处：《天津医科大学学报》2010年第2期242-244,251,共4页Journal of Tianjin Medical University

摘　　要：目的:探讨心磁图(MCG)在冠心病(CHD)诊断中的临床应用价值。方法:应用美国CardioMagImaging公司生产的CMI-2409型心磁图仪,分别对383例冠心病患者(冠状动脉造影显示至少1支冠状动脉主要分支狭窄≥50%)和110例非冠心病患者(冠状动脉造影无狭窄)进行心磁图检查,对MCG的7项参数T峰前磁向量、T峰前磁移动距离、T峰前磁向量变异率、T峰后磁向量、T峰后磁移动距离、T峰后磁向量变异率、T峰前后磁向量变化进行分析。结果:(1)冠心病组与非冠心病组MCG7项参数差异均具有显著性意义(P<0.01)。(2)T峰前磁向量、T峰前磁移动距离、T峰前磁向量变异率、T峰后磁向量、T峰后磁移动距离、T峰后磁向量变异率、T峰前后磁向量变化诊断冠心病的敏感性分别为40.73%、51.17%、50.39%、30.81%、52.74%、55.87%、31.59%,特异性分别为83.64%、71.82%、73.64%、90.91%、70.91%、71.82%、97.27%。MCG7项参数中任意3项以上阳性,诊断冠心病的敏感性为56.40%,特异性为90.91%。结论:MCG是一项无创性、对冠心病诊断有较高价值的检查方法。Objective： To evaluate the clinical application of magnetocardiography （MCG） in diagnosis of coronary heart disease （CHD）. Methods： MCG measurements were performed in 383 patients with CHD （coronary angiography showed that at least one major branch of coronary artery stenosis t〉 50%）and 110 patient with non-CHD （coronary arteriography negative） by CMI-2409 MCG instrument produted by CardioMag Imaging Company. Seven parameters of MCG were nanlyzed pre-peak repolarization angle, pre-peak repolarization trajectory, pre-peak repolarization angular deviation, post-peak repolarization angle, post-peak repolarization trajectory, post-peak repolarization angular deviation and pre-post angle change. Results： （i） Significant difference were found in seven parramenters of MCG between CHD and non-CHD group. （2） The diagnostic sensitivity of pre-angle, pre-trajectory, pre-angular deviation, post- angle, post-trajectory, post-angular deviation, pre-post angle change were 40.73%, 51.17%, 50.39%, 30.81%, 52.74%, 55.87%, 31.59% respeetively, the specificity were 83.64%, 71.82%, 73.64%, 90.91%, 70.91%, 71.82%, 97.27% respectively. Three or more paramenters were positive, the sensitivity for diagnosis of coronary heart disease was 56.40% and specificity was 90.91%. Conclusion： MCG is a noninvasive, higher values method for the diagnosis of CHD.

关 键 词：心磁图 冠心病 诊断 

分 类 号：R541.4[医药卫生—心血管疾病]