尿白蛋白排泄率与多囊卵巢综合征的关系  

The correlation between urinary albumin excretion rate and polycystic ovarian syndrome

作　　者：王亚男[1] 李晓文[2] 王德华[1] 苑亚茹[2] 

机构地区：[1]天津医科大学总医院妇产科,天津300052 [2]天津市第五中心医院

出　　处：《天津医科大学学报》2010年第2期270-272,共3页Journal of Tianjin Medical University

摘　　要：目的:评价多囊卵巢综合征(PCOS)患者尿白蛋白排泄率(UAER)与其临床特征、性激素水平以及某些代谢指标的相关性。方法:对57例PCOS患者进行临床评估、血清性激素水平及尿白蛋白排泄率的测定。结果:经Pearson相关分析后UAER与体重指数、腰臀比、收缩压、舒张压、空腹血糖、空腹胰岛素、甘油三酯、稳态模型胰岛素抵抗指数(HOMA-IR)成正相关,与高密度脂蛋白成负相关;多元线性逐步回归分析提示:HOMA-IR指数是PCOS患者微量白蛋白尿的独立危险因素。结论:PCOS患者的UAER与其它易导致心血管系统疾病的因素有相关性,对此指标的正确评定将有益于指导临床治疗。Objective： To evaluate urinary albumin excretion rate （UAER） in women with polycystic ovarian syndrome （PCOS） in relation to their clinical,endocrine,and metabolic indexes. Methods： 57 subjucts were assessed by clinical feature, blood hormonal testing and urinary albumin excretion rate testing . Results： Pearson correlation analysis indicated that, urinary albumin excretion rate positively correlated with body mass index, waist-hip ratio,systolic blood pressure, diastolic blood pressure, fasting glucose,fasting insulin, triglycerides, HOMA-IR, and negatively correlated with high-density lipoprotein; Multiple linear stepwise regression analysis showed that HOMA-IR as an independent factor affected UAER. Conclusion： UAER in women with PCOS correlates with other cardiovascular risk factors,if assessed correctly, it will be beneficial to clinical treatment.

关 键 词：多囊卵巢综合征 尿白蛋白排泄率 胰岛素抵抗 心血管疾病 

分 类 号：R711.75[医药卫生—妇产科学]