猪生殖-呼吸道综合征病毒抗原在死胎及新生仔猪体内的分布  

Distribution of Porcine Reproductive and Respiratory Syndrome Virus Antigen in Stillborn Fetuses and Live born Piglets

作　　者：吴东来[1] 郭宝清[1] 李桂芝[1] 蔡雪晖[1] 王继科[1] 褚桂芳[1] 

机构地区：[1]中国农业科学院哈尔滨兽医研究所

出　　处：《中国预防兽医学报》1999年第2期128-129,共2页Chinese Journal of Preventive Veterinary Medicine

摘　　要：应用抗猪生殖－呼吸道综合征病毒（ＰＲＲＳＶ）单克隆抗体所做的间接免疫荧光抗体试验（ＩＦＡ），对人工接种ＰＲＲＳＶ的３头妊娠母猪所产９头死胎和２头新生仔猪体内的ＰＲＲＳＶ抗原分布进行了观察。结果表明，ＰＲＲＳＶ抗原在死胎主要分布于脾脏（９／９）和淋巴结（３／４）的巨噬细胞内，而少见于肺（２／９）和肾（０／９）等其他脏器。但新生仔猪则仅在肺脏（２／２）的巨噬细胞内检出了ＰＲＲＳＶ抗原。此结果说明ＰＲＲＳＶ可通过胎盘屏障垂直传播给胎儿。The distribution of Porcine Reproductive and Respiratory Syndrome Virus(PRRSV) antigen in 9 stillborn fetuses and 2 live born piglets transplacentally infected with PRRSV were examined by indirect immunoflourescent antibody test (IFA) using a monoclonal antibody against PRRSV In stillborn fetuses,PRRSV antigens mainly distributed in macrophages in spleens (9/9) and lymph nodes (3/4),but rarely were detected in lungs (2/9),kidneys(0/9) and other organs In live born pigs,however,PRRSV antigens were only detected in macrophages in lungs (2/2) The results suggested that PRRSV could transplacentally transfer to the fetuses,and tissuetropic of PRRSV has some deferences between stillborn fetuses and live born pigs

关 键 词：抗原分布 死胎 新生仔猪 PRRS 猪 

分 类 号：S858.285.3[农业科学—临床兽医学]