网织血小板在特发性血小板减少性紫癜中的临床价值  

The Clinical Value of Reticulated Platelets in Idiopathic Thrombocytopenic Purpura

作　　者：肖成华[1] 冯建明[2] 李文倩[2] 

机构地区：[1]青海大学医学院,810007 [2]青海省人民医院,810007

出　　处：《青海医药杂志》2010年第4期1-3,共3页Qinghai Medical Journal

摘　　要：目的:探讨网织血小板(RP)的百分比对特发性血小板减少性紫癜(ITP)的临床意义。方法:采用流式细胞仪测定30例ITP患者治疗前后外周血中RP的百分率,并与15例再生障碍性贫血(AA)患者、30例正常体检者进行比较。结果:30例ITP病人治疗前网织血小板百分比(RP%)为(27.2±8.3)%,治疗后的ITP病人RP%为(8.3±2.4)%,治疗前后相比有统计学意义;正常对照组RP%为(8.4±2.3)%,治疗前的ITP病人RP%明显高于正常对照组,治疗后的ITP病人RP%与正常对照组无差异;15例AA的RP%为(6.3±2.1)%,与正常对照组相比差异无统计学意义(P>0.05)。结论:外周血RP%测定,有助于ITP的诊断及治疗监测。Objective：To characterize the clinical significance of the percentage of reticulated platelets（RP）on idiopathic thrombocytopenic purpura（ITP）.Methods：We measured RP percentage in peripheral blood using the flow cytometry for 30 cases of ITP patients before and after treatment,and the results were compared with the data of 15 cases of aplastic anemia（AA）group and 30 normal healthy control group.Results：The average percentage of RP（RP %）in pre-and post-treatment in the ITP group was 27.2%±8.3% and8.3%±2.4% respectively（P〈0.05）.RP% was higher before treatment in the ITP group as compared with the control group8.4%±2.3%,P〈0.05;but no different in RP% between the ITP patients after treatment and the control group（P〉0.05）,and no difference in RP% between the AA group 6.3%±2.1% and the controls（P〉0.05）.Conclusions：Measurement of the percentage of RP in peripheral blood would contribute to diagnosis and treatment of ITP.

关 键 词：血小板减少 网织血小板 特发性血小板减少性紫瘢 

分 类 号：R554.6[医药卫生—血液循环系统疾病]