黄芪注射液对2种力竭运动大鼠血清肌酸激酶及其同工酶活性的影响  

Effect of Radix Astragali Injection on Creatine Kinase and Isoenzyme of Creatine Kinase Level in Rat Serum After Two Kind of Exhausting Exercises

作　　者：李永峰[1] 韩勇[1] 郭勇力[1] 王传军[1] 李晔[1] 

机构地区：[1]山东体育学院日照校区基础理论系,山东日照276826

出　　处：《中国实验方剂学杂志》2010年第6期224-226,230,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨黄芪注射液对两种力竭运动大鼠血清肌酸激酶(CK)及其同工酶的影响,为减轻运动性肌肉损伤寻找有效的方法。方法:将50只大鼠随机均分为5组,各10只:安静对照组、一次性力竭运动组、多次力竭运动组、服药+一次性力竭运动组、服药+多次力竭运动组。经过4周的实验后,测血清CK及其同工酶的含量。结果:一次力竭和多次力竭大鼠血清CK及其同工酶活性显著增高(P<0.01),黄芪注射液对一次力竭和多次力竭大鼠血清CK及其同工酶活性有降低作用(P<0.01)。结论:黄芪注射液对减轻2种力竭运动引起的肌肉损伤均有很好的作用。Objective：In order to search potent means for exercise-induced muscle damage,effect of Radix Astragali injection on serum creatine kinase（CK） and isoenzyme of creatine kinase（CK-MM） level in rats after two kind of Exhausting Exercises was observed.Method：50 Wister Rats were randomLy divided into 5 group：normal control group（n = 10）,once exhausting exercise group（n = 10）,multiple exhausting exercises group（n = 10）,Radix Astragali injection filled the stomach and once exhausting exercise group（n = 10）,Radix Astragali injection filled the stomach and multiple exhausting exercises group（n = 10）.After 4 weeks test,serum CK and CK-MM were tested.Result：Afer exhausting exercise,CK and CK-MM in blood serum as well as were higher than that in normal control group（P〈 0.01）.the change was prevented by Radix Astragali injection（P 〈0.01）.Conclusion：Radix Astragali injection may help reduce exercise-induced muscle damage afer two kind of exhausting exercises.

关 键 词：黄芪注射液 力竭运动 肌酸激酶 同工酶 

分 类 号：R285.5[医药卫生—中药学]