2005年-2008年宁波地区孕妇TORCH-IgM检测结果分析  

Analysis on TORCH-IgM antibodies detected in Ningbo City from 2005 to 2008

作　　者：徐苹[1] 倪建萍[1] 卢文波[1] 

机构地区：[1]宁波市妇女儿童医院检验科,浙江宁波315012

出　　处：《中国优生与遗传杂志》2010年第6期73-74,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解宁波地区孕妇中TORCH-IgM的阳性率,探讨选择性TORCH-IgM筛查的临床价值,为有效预防TORCH感染提供科学依据。方法采用酶联免疫法(ELISA)检测9385例孕妇血清的TORCH-IgM抗体水平,根据有无高危因素比较不同孕妇的血清抗体阳性率。结果高危因素组的孕妇TORCH-IgM阳性率分别为:TOX-IgM 1.02%、RV-IgM 1.86%、CMV-IgM 3.76%、HSVⅠ-IgM 7.75%、HSVⅡ-IgM 3.85%;无高危因素组的孕妇TORCH-IgM阳性率分别为:TOX-IgM 0.35%、RV-IgM 1.23%、CMV-IgM 2.26%、HSVⅠ-IgM 5.23%、HSVⅡ-IgM 2.64%;两组比较差异有显著性(P<0.05)。结论对具有高危因素的孕妇应常规进行TORCH-IgM筛查,以便及早发现宫内感染,干预不良妊娠。Objective： To investigate the positive rate of TORCH immunoglobulin M （TORCH - IgM ） antibodies in pregnant women in Ningbo city and to explore the clinical value of selective TORCH - IgM screening. Methods ： The level of serum TORCH - IgM antibodies were detected in 9385 pregnant women using enzyme linked -Immuno -sorbent assay （ELISA） , and the positive rates of serum TORCH - IgM antibodies in different women were compared according to whether they had the high risk factors or not. Resuits： The positive rates of serum TORCH - IgM antibodies in the women with the high risk factors were as follows： TOX - IgM 1.02% , RV - IgM 1.86% , CMV - IgM 3.76% , HSV I - IgM 7.75% , HSV Ⅱ - IgM 3.85% , respectively. Those in the women without the high risk factors were as follows： TOX -IgM 0. 35% , RV - IgM 1.23%, CMV - IgM 2. 26%, HSV I - IgM 5.23%, HSV Ⅱ -IgM 2. 64%, respectively. There was significant deviation between the two groups （ P 〈 0.05 ）. Conclusion： Pregnant women with the high risk factors should routinely receive TORCH - IgM antibodies screening so as to find in trauterine infection early as possibly and intervene the unhealthy pregnancy.

关 键 词：孕妇 TORCH 感染率 

分 类 号：R446.6[医药卫生—诊断学]