2006～2009年我院309例药品不良反应报告分析  

ADR Case Report in Our Hospital During 2006～2009:An Analysis of 309 Cases

作　　者：曾斌[1] 高厚明[1] 刘志承[1] 刘凯南[1] 

机构地区：[1]深圳市中医院药学部,深圳市518033

出　　处：《中国医院用药评价与分析》2010年第6期556-558,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨我院药品不良反应(ADR)的发生因素、一般规律及特征,为临床安全、合理用药提供参考。方法:对收集到的309例ADR,按患者年龄、性别、给药途径、ADR程度、药品类型、ADR涉及器官或系统及临床表现等进行分类统计与分析。结果:涉及ADR的药品共有309种,抗生素居首位,其次为中成药;静脉注射引发的ADR为205例(占66.34%);ADR可发生于人体各个系统,但主要为变态反应,以皮肤及其附件损害最为严重,其次是神经系统损害;新的一般的ADR52例,新的严重的ADR1例。结论:医务人员在临床药品使用中应重视和加强ADR监测,结合ADR发生特点,合理用药,从而减少或避免药品不良反应的发生。OBJECTIVE：To probe into the factors,regular pattern and characteristics of adverse drug reactions（ADRs） occurred in our hospital for references of safe and rational clinical medication.METHODS：A total of 309 ADR reports collected in our hospital were statistically analyzed in respect of age and sex of patients,route of administration,ADR degree,drug category,organs involved and clinical manifestations etc.RESULTS：ADR involved drugs totaled 309 kinds,of which anti-infective agents occupied the first place,followed by Chinese patent medicines.205 ADR cases（66.34%） were induced by intravenous route.ADR occurred systemically and were characterized predominantly by allergic reactions of skin and its appendants,followed by lesions of nervous system.52 were new but common ADR cases,while 1 was new severe case.CONCLUSION：Medical staff should attach great importance to the monitoring of ADR and to achieve rational drug use based on the characteristics of ADR so as to lessen and avoid the incidence of ADR.

关 键 词：药品不良反应 报告 分析 

分 类 号：R969.3[医药卫生—药理学]